AIMC Topic: Blood Protein Electrophoresis
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Quantitative abnormalities in the β-region of the electrophoretic profile of serum proteins as predictive markers of monoclonality: Machine learning for monoclonality prediction.
Clinical biochemistry
Feb 1, 2025
OBJECTIVE OF THE STUDY: To develop a machine learning algorithm aimed at predicting the presence of a monoclonal (M-) protein when the β-globulin fraction is elevated.
Performance and efficiency of machine learning models in analyzing capillary serum protein electrophoresis.
Clinica chimica acta; international journal of clinical chemistry
Jan 26, 2025
BACKGROUND AND OBJECTIVE: Serum protein electrophoresis (SPEP) plays a critical role in diagnosing diseases associated with M-proteins. However, its clinical application is limited by a heavy reliance on experienced experts.
Artificial intelligence aided serum protein electrophoresis analysis of Finnish patient samples: Retrospective validation.
Clinica chimica acta; international journal of clinical chemistry
Dec 9, 2024
BACKGROUND AND AIMS: Serum protein electrophoresis interpretation requires a substantial amount of manual work. In 2020, Chabrun et al. created a machine learning method called SPECTR for the task. We aimed to validate and test the SPECTR method agai...
Expert-level detection of M-proteins in serum protein electrophoresis using machine learning.
Clinical chemistry and laboratory medicine
Jun 17, 2024
OBJECTIVES: Serum protein electrophoresis (SPE) in combination with immunotyping (IMT) is the diagnostic standard for detecting monoclonal proteins (M-proteins). However, interpretation of SPE and IMT is weakly standardized, time consuming and invest...
Artificial intelligence in serum protein electrophoresis: history, state of the art, and perspective.
Critical reviews in clinical laboratory sciences
Nov 1, 2023
Serum protein electrophoresis (SPEP) is a valuable laboratory test that separates proteins from the blood based on their electrical charge and size. The test can detect and analyze various protein abnormalities, and the interpretation of graphic SPEP...
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