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Effect of Mast Cell Chymase on Activation, Proliferation and Transdifferentiation of Hepatic Stellate Cells.

Hepato-gastroenterology 26902046
BACKGROUND/AIMS: This work aims to observe the effects of mast cell (MC) chymase on activation, proliferation and transdifferentiation of hepatic stellate cells (HSCs) and to discuss the role of chymase in development of liver fibrosis.
Actins Animals Blotting, Western Cell Proliferation Cell Transdifferentiation Cells, Cultured Chymases Collagen Type I Hepatic Stellate Cells Male Mast Cells Rats Rats, Wistar Real-Time Polymerase Chain Reaction RNA, Messenger Transforming Growth Factor beta1
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