AIMC Topic: Hepatic Stellate Cells
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Curcumin Modulates NOX Gene Expression and ROS Production via P-Smad3C in TGF-β-Activated Hepatic Stellate Cells.
Iranian biomedical journal
Oct 28, 2023
BACKGROUND: Liver fibrosis, associated with hepatic stellate cells (HSCs), occurs when a healthy liver sustains damage, thereby impairing its function. NADPH oxidases (NOXs), specifically isoforms 1, 2, and 4, play a role in reactive oxygen species (...
Apoptosis of rat hepatic stellate cells induced by diallyl trisulfide and proteomics profiling in vitro.
Canadian journal of physiology and pharmacology
Nov 18, 2016
Diallyl trisulfide (DATS), a major garlic derivative, inhibits cell proliferation and triggers apoptosis in a variety of cancer cell lines. However, the effects of DATS on hepatic stellate cells (HSCs) remain unknown. The aim of this study was to ana...
Modified citrus pectin stops progression of liver fibrosis by inhibiting galectin-3 and inducing apoptosis of stellate cells.
Canadian journal of physiology and pharmacology
Dec 16, 2015
Modified citrus pectin (MCP) is a pH modified form of the dietary soluble citrus peel fiber known as pectin. The current study aims at testing its effect on liver fibrosis progression. Rats were injected with CCl4 (1 mL/kg, 40% v/v, i.p., twice a wee...
Solubility
Hot Temperature
Citrus
Dietary Fiber
Lipid Peroxidation
Fruit
Carbon Tetrachloride
Pectins
Liver Cirrhosis, Experimental
Rats, Sprague-Dawley
Apoptosis
Dietary Supplements
Hepatic Stellate Cells
Hydrogen-Ion Concentration
Disease Progression
Liver
Galectin 3
Oxidative Stress
Biomarkers
Antioxidants
Animals
Male
Anti-hepatofibrosis effect of Allium senescens in activated hepatic stellate cells and thioacetamide-induced fibrosis rat model.
Pharmaceutical biology
Dec 1, 2018
CONTEXT: Allium senescens Linn. (Liliaceae) (ASL) has been traditionally used in Korea and other Asian countries for improving digestive and liver functions.
[Experimental study on effect of model on hepatic fibrosis with Aralia chinesis].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Nov 1, 2015
Hepatic fibrosis models were induced by CCl4 in rats. To explore vascular endothelial growth factor (VEGF), transforming growth factor-beta1 (TGFβ1) mRNA expression and bcl-2, Bax protein expression levels of intervention and explore the mechanism of...
[Effects of Ethanol Extracts of Phellinus lonicerinus on Hepatic Stellate Cells of Fibrosis Liver in Rats].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
Aug 1, 2015
OBJECTIVE: To study the effects of ethanol extracts of Phellinus lonicerinus on hepatic stellate cells of fibrosis liver in rats.
Effect of Mast Cell Chymase on Activation, Proliferation and Transdifferentiation of Hepatic Stellate Cells.
Hepato-gastroenterology
Jun 1, 2015
BACKGROUND/AIMS: This work aims to observe the effects of mast cell (MC) chymase on activation, proliferation and transdifferentiation of hepatic stellate cells (HSCs) and to discuss the role of chymase in development of liver fibrosis.
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