AIMC Topic: Computer Simulation

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[Simulators and simulation for advanced training in orthopedic and trauma surgery : An overview].

Unfallchirurgie (Heidelberg, Germany)
Simulators and immersive technologies, such as virtual reality and augmented reality are becoming increasingly more important for training in orthopedic and trauma surgery. They enable safe and standardized training of surgical skills and contribute ...

A Review of In Silico Approaches for Discovering Natural Viral Protein Inhibitors in Aquaculture Disease Control.

Journal of fish diseases
Viral diseases pose a significant threat to the sustainability of global aquaculture, causing economic losses and compromising food security. Traditional control methods often demonstrate limited effectiveness, highlighting the need for alternative a...

Uncovering water conservation patterns in semi-arid regions through hydrological simulation and deep learning.

PloS one
Under the increasing pressure of global climate change, water conservation (WC) in semi-arid regions is experiencing unprecedented levels of stress. WC involves complex, nonlinear interactions among ecosystem components like vegetation, soil structur...

Risk assessment of potentially toxic elements and mapping of groundwater pollution indices using soft computer models in an agricultural area, Northeast Algeria.

Journal of hazardous materials
Groundwater (GW) quality and contamination by potentially toxic elements (PTEs) are major concerns for environmental sustainability, particularly in arid regions. The aim of this study was to assess the human health risks associated with GW contamina...

A novel seven-tier framework for the classification of MEFV missense variants using adaptive and rigid classifiers.

Scientific reports
There is a great discrepancy between the clinical categorization of MEFV gene variants and in silico tool predictions. In this study, we developed a seven-tier classification system for MEFV missense variants of unknown significance and recommended a...

Initial characterization of a novel dual-robot orthovoltage radiotherapy system.

Biomedical physics & engineering express
Adequate access to radiotherapy is a critical global concern affecting low-resource settings such as low- and middle-income countries and rural regions. We propose to reduce this disparity by developing a novel low-cost radiotherapy device that treat...

Understanding the Spatio-Temporal Coupling of Spikes and Spindles in Focal Epilepsy Through a Network-Level Computational Model.

International journal of neural systems
The electrophysiological findings have shown that epileptiform spikes triggering sleep spindles within 1[Formula: see text]s across multiple channels are commonly observed during sleep in focal epilepsy (FE). Such spatio-temporal couplings of spikes ...

Quantitative multislice and jointly optimized rapid CEST for in vivo whole-brain imaging.

Magnetic resonance in medicine
PURPOSE: To develop a quantitative multislice chemical exchange saturation transfer (CEST) schedule optimization and pulse sequence that reduces the loss of sensitivity inherent to multislice sequences.

A deep learning approach to multi-fiber parameter estimation and uncertainty quantification in diffusion MRI.

Medical image analysis
Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors such as va...

Employing Automated Machine Learning (AutoML) Methods to Facilitate the ADMET Properties Prediction.

Journal of chemical information and modeling
The rationale for using ADMET prediction tools in the early drug discovery paradigm is to guide the design of new compounds with favorable ADMET properties and ultimately minimize the attrition rates of drug failures. Artificial intelligence (AI) in ...