AIMC Topic: Finite Element Analysis

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Role of tight junctions in three-dimensional mechanical model of blood-brain barrier.

Journal of biomechanics
The increasing prevalence of central nervous system (CNS) disorders has imposed a significant social and economic burden on healthcare systems. The blood-brain barrier (BBB) presents a major challenge for effective drug delivery to the brain, hinderi...

Efficient, Robust, and Accurate CNN Predictor for Neuronal Activation in Directional Deep Brain Stimulation.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
The programming of clinical deep brain stimulation (DBS) systems involves numerous combinations of stimulation parameters, such as stimulus amplitude, pulse width, and frequency. As more complex electrode designs, such as directional electrodes, are ...

Multi-objective optimization framework to plan laser ablation procedure for prostate tumors through a genetic algorithm.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVES: Prostate cancer is the most common form of cancer in the male population. While the survival rate is high, many patients undergo surgical procedures for prostate cancer that might never progress to clinical significance. As...

A high-throughput framework for predicting three-dimensional structural-mechanical relationships of human cranial bones using a deep learning-based method.

Journal of the mechanical behavior of biomedical materials
Cranial bone injuries significantly impact human health, potentially leading to death or permanent disability, and mechanical responses are crucial predictors of cranial damage. Predicting mechanical responses through medical imaging is an efficient ...

Dynamic simulation of knee joint mechanics: individualized multi-moment finite element modelling of patellar tendon stress during landing.

Journal of biomechanics
Patellar tendinopathy is prevalent in sports requiring high jumping demands, and understanding the in vivo biomechanical behavior of the patellar tendon (PT) during landing is crucial for developing effective injury prevention and rehabilitation stra...

Deep learning-aided segmentation combined with finite element analysis reveals a more natural biomechanic of dinosaur fossil.

Scientific reports
Finite element analysis (FEA), a biomechanical simulation technique capable of providing direct mechanical visualization for CT-based digital models, has been extensively applied to fossil image datasets to address key evolutionary questions in paleo...

Parametric cushioning lattice insole based on finite element method and machine learning: A preliminary computational analysis.

Journal of biomechanics
The cushioning performance of insole has always been a critical consideration in its design. While the development of intelligent methods and the emergence of additive manufacturing (AM) technology have enhanced design freedom and convenience, a stan...

Surrogate Model Development for Digital Experiments in Welding.

Journal of visualized experiments : JoVE
The manufacturing industry heavily relies on welding processes to join materials, forming integral components across various sectors. Many aspects will influence the quality of the weld and finally affect the structure integrity of the weldment. Weld...

Modelling fourth-order hyperelasticity in soft solids using physics informed neural networks without labelled data.

Brain research bulletin
Mild traumatic brain injury can result from shear shock wave formation in the brain in the event of a head impact like in contact sports, road traffic accidents, etc. These highly nonlinear deformations are modelled by a fourth-order Landau hyperelas...

Design of a Soft Robotic Artificial Cardiac Wall.

Artificial organs
BACKGROUND: In cardiovascular engineering, the recent introduction of soft robotic technologies sheds new light on the future of implantable cardiac devices, enabling the replication of complex bioinspired architectures and motions. To support human ...