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DEAD-box RNA Helicases

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LBSizeCleav: improved support vector machine (SVM)-based prediction of Dicer cleavage sites using loop/bulge length.

BMC bioinformatics 27887571
BACKGROUND: Dicer is necessary for the process of mature microRNA (miRNA) formation because the Dicer enzyme cleaves pre-miRNA correctly to generate miRNA with correct seed regions. Nonetheless, the mechanism underlying the selection of a Dicer cleav...
Algorithms Base Sequence Bayes Theorem DEAD-box RNA Helicases Humans MicroRNAs Nucleic Acid Conformation Ribonuclease III RNA Precursors Software Support Vector Machine
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Enhancing HCV NS3 Inhibitor Classification with Optimized Molecular Fingerprints Using Random Forest.

International journal of molecular sciences 40141322
The classification of Hepatitis C virus (HCV) NS3 inhibitors is essential for identifying potential antiviral agents through computational methods. This study aims to develop an optimized machine learning (ML) model using random forest (RF) and molec...
Antiviral Agents DEAD-box RNA Helicases Drug Discovery Hepacivirus Humans Machine Learning Nucleoside-Triphosphatase Protease Inhibitors Random Forest Serine Endopeptidases Viral Nonstructural Proteins Viral Proteases
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