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Homeostasis

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Effects of sevoflurane versus propofol on cerebral autoregulation during anaesthesia for robot-assisted laparoscopic prostatectomy.

Anaesthesia and intensive care
Robot-assisted laparoscopic prostatectomy requires a pneumoperitoneum combined with steep Trendelenburg positioning, and these conditions can be associated with impairment of cerebral autoregulation. The objective of this study was to determine if ch...

Relating local connectivity and global dynamics in recurrent excitatory-inhibitory networks.

PLoS computational biology
How the connectivity of cortical networks determines the neural dynamics and the resulting computations is one of the key questions in neuroscience. Previous works have pursued two complementary approaches to quantify the structure in connectivity. O...

Modulating autophagy to treat diseases: A revisited review on in silico methods.

Journal of advanced research
BACKGROUND: Autophagy refers to the conserved cellular catabolic process relevant to lysosome activity and plays a vital role in maintaining the dynamic equilibrium of intracellular matter by degrading harmful and abnormally accumulated cellular comp...

Intrinsic neural diversity quenches the dynamic volatility of neural networks.

Proceedings of the National Academy of Sciences of the United States of America
Heterogeneity is the norm in biology. The brain is no different: Neuronal cell types are myriad, reflected through their cellular morphology, type, excitability, connectivity motifs, and ion channel distributions. While this biophysical diversity enr...

Emerging technologies in adipose tissue research.

Adipocyte
Technologies are transforming the understanding of adipose tissue as a complex and dynamic tissue that plays a critical role in energy homoeostasis and metabolic health. This mini-review provides a brief overview of the potential impact of novel tech...

Using AI to Write a Review Article Examining the Role of the Nervous System on Skeletal Homeostasis and Fracture Healing.

Current osteoporosis reports
PURPOSE OF REVIEW: Three review articles have been written that discuss the roles of the central and peripheral nervous systems in fracture healing. While content among the articles is overlapping, there is a key difference between them: the use of a...

Homeostasis imbalance process ontology: a study on COVID-19 infectious processes.

BMC medical informatics and decision making
BACKGROUND: One significant challenge in addressing the coronavirus disease 2019 (COVID-19) pandemic is to grasp a comprehensive picture of its infectious mechanisms. We urgently need a consistent framework to capture the intricacies of its complicat...

Emergence of integrated behaviors through direct optimization for homeostasis.

Neural networks : the official journal of the International Neural Network Society
Homeostasis is a self-regulatory process, wherein an organism maintains a specific internal physiological state. Homeostatic reinforcement learning (RL) is a framework recently proposed in computational neuroscience to explain animal behavior. Homeos...

Automated model discovery for tensional homeostasis: Constitutive machine learning in growth and remodeling.

Computers in biology and medicine
We present a built-in physics neural network architecture, known as inelastic Constitutive Artificial Neural Network (iCANN), to discover the inelastic phenomenon of tensional homeostasis. In this course, identifying the optimal model and material pa...

Soft Biological Actuators for Meter-Scale Homeostatic Biohybrid Robots.

Chemical reviews
Skeletal muscle's elegant protein-based architecture powers motion throughout the animal kingdom, with its constituent actomyosin complexes driving intra- and extra-cellular motion. Classical motors and recently developed soft actuators cannot match ...