AIMC Topic: Diabetic Foot

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Utilizing bioinformatics and machine learning to identify CXCR4 gene-related therapeutic targets in diabetic foot ulcers.

Frontiers in endocrinology Feb 7, 2025
BACKGROUND: Diabetic foot ulcers (DFUs) are a serious complication of diabetes mellitus that manifests as chronic, non-healing wounds that have a significant impact on patients quality of life. Identifying key molecular targets associated with DFUs c...
Humans Computational Biology Databases, Genetic Wound Healing Receptors, CXCR4 Protein Interaction Maps Diabetic Foot Gene Regulatory Networks Machine Learning Gene Expression Profiling
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An explainable deep learning model for diabetic foot ulcer classification using swin transformer and efficient multi-scale attention-driven network.

Scientific reports Feb 3, 2025
Diabetic Foot Ulcer (DFU) is a severe complication of diabetes mellitus, resulting in significant health and socio-economic challenges for the diagnosed individual. Severe cases of DFU can lead to lower limb amputation in diabetic patients, making th...
Algorithms Deep Learning Diabetic Foot Humans Neural Networks, Computer
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E-DFu-Net: An efficient deep convolutional neural network models for Diabetic Foot Ulcer classification.

Biomolecules & biomedicine Jan 14, 2025
The Diabetic Foot Ulcer (DFU) is a severe complication that affects approximately 33% of diabetes patients globally, often leading to limb amputation if not detected early. This study introduces an automated approach for identifying and classifying D...
Deep Learning Convolutional Neural Networks Diabetic Foot Humans Neural Networks, Computer
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Advances in Machine Learning-Aided Thermal Imaging for Early Detection of Diabetic Foot Ulcers: A Review.

Biosensors Dec 13, 2024
The prevention and early warning of foot ulcers are crucial in diabetic care; however, early microvascular lesions are difficult to detect and often diagnosed at later stages, posing serious health risks. Infrared thermal imaging, as a rapid and non-...
Thermography Diabetic Foot Early Diagnosis Humans Machine Learning
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A few-shot diabetes foot ulcer image classification method based on deep ResNet and transfer learning.

Scientific reports Dec 2, 2024
Diabetes foot ulcer (DFU) is one of the common complications of diabetes patients, which may lead to infection, necrosis and even amputation. Therefore, early diagnosis, classification of severity and related treatment are crucial for the patients. C...
Humans Image Processing, Computer-Assisted Diabetic Foot Neural Networks, Computer Deep Learning
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SDC4 protein action and related key genes in nonhealing diabetic foot ulcers based on bioinformatics analysis and machine learning.

International journal of biological macromolecules Nov 17, 2024
Diabetic foot ulcers (DFU) is a complication associated with diabetes characterised by high morbidity, disability, and mortality, involving chronic inflammation and infiltration of multiple immune cells. We aimed to identify the critical genes in non...
Transcriptome Humans Gene Expression Regulation Computational Biology Gene Expression Profiling Machine Learning Single-Cell Analysis Diabetic Foot Syndecan-4
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Machine learning-driven discovery of novel therapeutic targets in diabetic foot ulcers.

Molecular medicine (Cambridge, Mass.) Nov 14, 2024
BACKGROUND: To utilize machine learning for identifying treatment response genes in diabetic foot ulcers (DFU).
Wound Healing Diabetic Foot Calcium-Binding Proteins Single-Cell Analysis Gene Expression Profiling Humans Computational Biology Transcriptome Machine Learning Female Male Biomarkers
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DFUCare: deep learning platform for diabetic foot ulcer detection, analysis, and monitoring.

Frontiers in endocrinology Sep 23, 2024
INTRODUCTION: Diabetic foot ulcers (DFUs) are a severe complication among diabetic patients, often leading to amputation or even death. Early detection of infection and ischemia is essential for improving healing outcomes, but current diagnostic meth...
Deep Learning Humans Diabetic Foot Algorithms
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Machine Learning-Driven discovery of immunogenic cell Death-Related biomarkers and molecular classification for diabetic ulcers.

Gene Sep 17, 2024
In this study, we redefine the diagnostic landscape of diabetic ulcers (DUs), a major diabetes complication. Our research uncovers new biomarkers linked to immunogenic cell death (ICD) in DUs by utilizing RNA-sequencing data of Gene Expression Omnibu...
Diabetic Foot Immunogenic Cell Death Humans Algorithms Machine Learning Biomarkers
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Interpretable machine learning models for detecting peripheral neuropathy and lower extremity arterial disease in diabetics: an analysis of critical shared and unique risk factors.

BMC medical informatics and decision making Jul 22, 2024
BACKGROUND: Diabetic peripheral neuropathy (DPN) and lower extremity arterial disease (LEAD) are significant contributors to diabetic foot ulcers (DFUs), which severely affect patients' quality of life. This study aimed to develop machine learning (M...
Middle Aged Humans Diabetic Neuropathies Female Lower Extremity Machine Learning Peripheral Arterial Disease Retrospective Studies Risk Factors Aged Diabetic Foot Male
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