AIMC Topic: DNA

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DeepBarcoding: Deep Learning for Species Classification Using DNA Barcoding.

IEEE/ACM transactions on computational biology and bioinformatics
DNA barcodes with short sequence fragments are used for species identification. Because of advances in sequencing technologies, DNA barcodes have gradually been emphasized. DNA sequences from different organisms are easily and rapidly acquired. There...

Biomacromolecule-Assisted Screening for Reaction Discovery and Catalyst Optimization.

Chemical reviews
Reaction discovery and catalyst screening lie at the heart of synthetic organic chemistry. While there are efforts at catalyst design using computation/artificial intelligence, at its core, synthetic chemistry is an experimental science. This review...

BERT-Promoter: An improved sequence-based predictor of DNA promoter using BERT pre-trained model and SHAP feature selection.

Computational biology and chemistry
A promoter is a sequence of DNA that initializes the process of transcription and regulates whenever and wherever genes are expressed in the organism. Because of its importance in molecular biology, identifying DNA promoters are challenging to provid...

DNA: Deeply Supervised Nonlinear Aggregation for Salient Object Detection.

IEEE transactions on cybernetics
Recent progress on salient object detection mainly aims at exploiting how to effectively integrate multiscale convolutional features in convolutional neural networks (CNNs). Many popular methods impose deep supervision to perform side-output predicti...

Single-cell specific and interpretable machine learning models for sparse scChIP-seq data imputation.

PloS one
MOTIVATION: Single-cell Chromatin ImmunoPrecipitation DNA-Sequencing (scChIP-seq) analysis is challenging due to data sparsity. High degree of sparsity in biological high-throughput single-cell data is generally handled with imputation methods that c...

Hyb4mC: a hybrid DNA2vec-based model for DNA N4-methylcytosine sites prediction.

BMC bioinformatics
BACKGROUND: DNA N4-methylcytosine is part of the restrictive modification system, which works by regulating some biological processes, for example, the initiation of DNA replication, mismatch repair and inactivation of transposon. However, using expe...

Using deep learning to detect digitally encoded DNA trigger for Trojan malware in Bio-Cyber attacks.

Scientific reports
This article uses Deep Learning technologies to safeguard DNA sequencing against Bio-Cyber attacks. We consider a hybrid attack scenario where the payload is encoded into a DNA sequence to activate a Trojan malware implanted in a software tool used i...

Characterizing collaborative transcription regulation with a graph-based deep learning approach.

PLoS computational biology
Human epigenome and transcription activities have been characterized by a number of sequence-based deep learning approaches which only utilize the DNA sequences. However, transcription factors interact with each other, and their collaborative regulat...

A Novel Adaptive Linear Neuron Based on DNA Strand Displacement Reaction Network.

IEEE/ACM transactions on computational biology and bioinformatics
Analog DNA strand displacement circuits can be used to build artificial neural network due to the continuity of dynamic behavior. In this study, DNA implementations of novel catalysis, novel degradation and adjustment reaction modules are designed an...

CapsProm: a capsule network for promoter prediction.

Computers in biology and medicine
Locating the promoter region in DNA sequences is of paramount importance in bioinformatics. This problem has been widely studied in the literature, but it has not yet been fully resolved. Some researchers have shown remarkable results using convoluti...