AIMC Topic: Drug Delivery Systems
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Drug-target interaction predication via multi-channel graph neural networks.
Briefings in bioinformatics
Jan 17, 2022
Drug-target interaction (DTI) is an important step in drug discovery. Although there are many methods for predicting drug targets, these methods have limitations in using discrete or manual feature representations. In recent years, deep learning meth...
An effective self-supervised framework for learning expressive molecular global representations to drug discovery.
Briefings in bioinformatics
Nov 5, 2021
How to produce expressive molecular representations is a fundamental challenge in artificial intelligence-driven drug discovery. Graph neural network (GNN) has emerged as a powerful technique for modeling molecular data. However, previous supervised ...
Tiny robots make big advances.
Science robotics
Mar 31, 2021
This special issue showcases developments in microactuation, microparticle control, and micro/nanorobots for biomedicine.
Dual-responsive biohybrid neutrobots for active target delivery.
Science robotics
Mar 24, 2021
Swimming biohybrid microsized robots (e.g., bacteria- or sperm-driven microrobots) with self-propelling and navigating capabilities have become an exciting field of research, thanks to their controllable locomotion in hard-to-reach areas of the body ...
Identifying drug-target interactions based on graph convolutional network and deep neural network.
Briefings in bioinformatics
Mar 22, 2021
Identification of new drug-target interactions (DTIs) is an important but a time-consuming and costly step in drug discovery. In recent years, to mitigate these drawbacks, researchers have sought to identify DTIs using computational approaches. Howev...
Application of deep learning methods in biological networks.
Briefings in bioinformatics
Mar 22, 2021
The increase in biological data and the formation of various biomolecule interaction databases enable us to obtain diverse biological networks. These biological networks provide a wealth of raw materials for further understanding of biological system...
Endoscopy-assisted magnetic navigation of biohybrid soft microrobots with rapid endoluminal delivery and imaging.
Science robotics
Mar 17, 2021
High-precision delivery of microrobots at the whole-body scale is of considerable importance for efforts toward targeted therapeutic intervention. However, vision-based control of microrobots, to deep and narrow spaces inside the body, remains a chal...
Sus scrofa
Spheroids, Cellular
Natural Orifice Endoscopic Surgery
Microtechnology
Drug Delivery Systems
3T3 Cells
Robotics
Animals
Microscopy, Electron, Scanning
Diagnostic Imaging
Male
Magnetics
Humans
Ultrasonography
Equipment Design
Computer Systems
Mice
Female
Rats
Endoscopy
Rats, Sprague-Dawley
An omics perspective on drug target discovery platforms.
Briefings in bioinformatics
Dec 1, 2020
The drug discovery process starts with identification of a disease-modifying target. This critical step traditionally begins with manual investigation of scientific literature and biomedical databases to gather evidence linking molecular target to di...
An agglutinate magnetic spray transforms inanimate objects into millirobots for biomedical applications.
Science robotics
Nov 18, 2020
Millirobots that can adapt to unstructured environments, operate in confined spaces, and interact with a diverse range of objects would be desirable for exploration and biomedical applications. The continued development of millirobots, however, requi...
Synthesis and evaluation of a novel nanosized anionic linear globular dendrimer G2-ciprofloxacin conjugate against prostate cancer.
Pakistan journal of pharmaceutical sciences
Nov 1, 2020
Prostate cancer is the second most common cancer in the world and the fifth cause of cancer deaths in men. Ciprofloxacin enables the inhabitation of the development of prostate cancer. In this regard, we plan to improve the anticancer effect of cipro...
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