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Four-Dimensional Computed Tomography

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Self-contained deep learning-based boosting of 4D cone-beam CT reconstruction.

Medical physics
PURPOSE: Four-dimensional cone-beam computed tomography (4D CBCT) imaging has been suggested as a solution to account for interfraction motion variability of moving targets like lung and liver during radiotherapy (RT) of moving targets. However, due ...

Simulated four-dimensional CT for markerless tumor tracking using a deep learning network with multi-task learning.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
INTRODUCTION: Our markerless tumor tracking algorithm requires 4DCT data to train models. 4DCT cannot be used for markerless tracking for respiratory-gated treatment due to inaccuracies and a high radiation dose. We developed a deep neural network (D...

Deep learning-based real-time volumetric imaging for lung stereotactic body radiation therapy: a proof of concept study.

Physics in medicine and biology
Due to the inter- and intra- variation of respiratory motion, it is highly desired to provide real-time volumetric images during the treatment delivery of lung stereotactic body radiation therapy (SBRT) for accurate and active motion management. In t...

Clinical practice vs. state-of-the-art research and future visions: Report on the 4D treatment planning workshop for particle therapy - Edition 2018 and 2019.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
The 4D Treatment Planning Workshop for Particle Therapy, a workshop dedicated to the treatment of moving targets with scanned particle beams, started in 2009 and since then has been organized annually. The mission of the workshop is to create an info...

GroupRegNet: a groupwise one-shot deep learning-based 4D image registration method.

Physics in medicine and biology
Accurate deformable four-dimensional (4D) (three-dimensional in space and time) medical images registration is essential in a variety of medical applications. Deep learning-based methods have recently gained popularity in this area for the significan...

A geometry-guided deep learning technique for CBCT reconstruction.

Physics in medicine and biology
Although deep learning (DL) technique has been successfully used for computed tomography (CT) reconstruction, its implementation on cone-beam CT (CBCT) reconstruction is extremely challenging due to memory limitations. In this study, a novel DL techn...

Synthetic pulmonary perfusion images from 4DCT for functional avoidance using deep learning.

Physics in medicine and biology
To develop and evaluate the performance of a deep learning model to generate synthetic pulmonary perfusion images from clinical 4DCT images for patients undergoing radiotherapy for lung cancer.. A clinical data set of 58 pre- and post-radiotherapyTc-...

A deep learning-based dual-omics prediction model for radiation pneumonitis.

Medical physics
PURPOSE: Radiation pneumonitis (RP) is the main source of toxicity in thoracic radiotherapy. This study proposed a deep learning-based dual-omics model, which aims to improve the RP prediction performance by integrating more data points and exploring...

Few-shot learning for deformable image registration in 4DCT images.

The British journal of radiology
OBJECTIVES: To develop a rapid and accurate 4D deformable image registration (DIR) approach for online adaptive radiotherapy.

Development of a deep learning-based patient-specific target contour prediction model for markerless tumor positioning.

Medical physics
PURPOSE: For pancreatic cancer patients, image guided radiation therapy and real-time tumor tracking (RTTT) techniques can deliver radiation to the target accurately. Currently, for the radiation therapy machine with kV X-ray imaging systems, interna...