AIMC Topic: Genetics, Medical
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Tracking medical genetic literature through machine learning.
Molecular genetics and metabolism
May 22, 2016
There has been remarkable progress in identifying the causes of genetic conditions as well as understanding how changes in specific genes cause disease. Though difficult (and often superficial) to parse, an interesting tension involves emphasis on ba...
Machine learning applications in genetics and genomics.
Nature reviews. Genetics
May 7, 2015
The field of machine learning, which aims to develop computer algorithms that improve with experience, holds promise to enable computers to assist humans in the analysis of large, complex data sets. Here, we provide an overview of machine learning ap...
Opportunities and challenges for the computational interpretation of rare variation in clinically important genes.
American journal of human genetics
Apr 1, 2021
Genome sequencing is enabling precision medicine-tailoring treatment to the unique constellation of variants in an individual's genome. The impact of recurrent pathogenic variants is often understood, however there is a long tail of rare genetic vari...
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