AIMC Topic: Machine Learning

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Machine Learning Model for Predicting Coronary Heart Disease Risk: Development and Validation Using Insights From a Japanese Population-Based Study.

JMIR cardio
BACKGROUND: Coronary heart disease (CHD) is a major cause of morbidity and mortality worldwide. Identifying key risk factors is essential for effective risk assessment and prevention. A data-driven approach using machine learning (ML) offers advanced...

Decoding Digital Discourse Through Multimodal Text and Image Machine Learning Models to Classify Sentiment and Detect Hate Speech in Race- and Lesbian, Gay, Bisexual, Transgender, Queer, Intersex, and Asexual Community-Related Posts on Social Media: Quantitative Study.

Journal of medical Internet research
BACKGROUND: A major challenge in sentiment analysis on social media is the increasing prevalence of image-based content, which integrates text and visuals to convey nuanced messages. Traditional text-based approaches have been widely used to assess p...

A novel predictive method for URS and laser lithotripsy using machine learning and explainable AI: results from the FLEXOR international database.

World journal of urology
PURPOSE: We developed Machine learning (ML) algorithms to predict ureteroscopy (URS) outcomes, offering insights into diagnosis and treatment planning, personalised care and improved clinical decision-making.

A machine learning-based prediction model for colorectal liver metastasis.

Clinical and experimental medicine
Colorectal liver metastasis (CRLM) is a primary factor contributing to poor prognosis and metastasis in colorectal cancer (CRC) patients. This study aims to develop and validate a machine learning (ML)-based risk prediction model using conventional c...

Machine Learning Classification of Chirality and Optical Rotation Using a Simple One-Hot Encoded Cartesian Coordinate Molecular Representation.

Journal of chemical information and modeling
Absolute stereochemical configurations and optical rotations were computed for 121,416 molecular structures from the QM9 quantum chemistry data set using density functional theory. A representation for the molecules was developed using Cartesian coor...

Exploring BERT for Reaction Yield Prediction: Evaluating the Impact of Tokenization, Molecular Representation, and Pretraining Data Augmentation.

Journal of chemical information and modeling
Predicting reaction yields in synthetic chemistry remains a significant challenge. This study systematically evaluates the impact of tokenization, molecular representation, pretraining data, and adversarial training on a BERT-based model for yield pr...

Rapid Adaptation of Chemical Named Entity Recognition Using Few-Shot Learning and LLM Distillation.

Journal of chemical information and modeling
Named entity recognition (NER) has been widely used in chemical text mining for the automatic identification and extraction of chemical entities. However, existing chemical NER systems primarily focus on scenarios with abundant training data, requiri...

EVOLVE: A Web Platform for AI-Based Protein Mutation Prediction and Evolutionary Phase Exploration.

Journal of chemical information and modeling
While predicting structure-function relationships from sequence data is fundamental in biophysical chemistry, identifying prospective single-point and collective mutation sites in proteins can help us stay ahead in understanding their potential effec...

MHNfs: Prompting In-Context Bioactivity Predictions for Low-Data Drug Discovery.

Journal of chemical information and modeling
Today's drug discovery increasingly relies on computational and machine learning approaches to identify novel candidates, yet data scarcity remains a significant challenge. To address this limitation, we present , an application specifically designed...

Evaluating Molecular Similarity Measures: Do Similarity Measures Reflect Electronic Structure Properties?

Journal of chemical information and modeling
The rapid adoption of big data, machine learning (ML), and generative artificial intelligence (AI) in chemical discovery has heightened the importance of quantifying molecular similarity. Molecular similarity, commonly assessed as the distance betwee...