AIMC Topic: Machine Learning

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User-centred design for machine learning in health care: a case study from care management.

BMJ health & care informatics
OBJECTIVES: Few machine learning (ML) models are successfully deployed in clinical practice. One of the common pitfalls across the field is inappropriate problem formulation: designing ML to fit the data rather than to address a real-world clinical p...

Identification of Patients With Metastatic Prostate Cancer With Natural Language Processing and Machine Learning.

JCO clinical cancer informatics
PURPOSE: Understanding treatment patterns and effectiveness for patients with metastatic prostate cancer (mPCa) is dependent on accurate assessment of metastatic status. The objective was to develop a natural language processing (NLP) model for ident...

Standardization of Artificial Intelligence Development in Radiotherapy.

Seminars in radiation oncology
Application of Artificial Intelligence (AI) tools has recently gained interest in the fields of medical imaging and radiotherapy. Even though there have been many papers published in these domains in the last few years, clinical assessment of the pro...

Artificial Intelligence for Outcome Modeling in Radiotherapy.

Seminars in radiation oncology
Outcome modeling plays an important role in personalizing radiotherapy and finds applications in specialized areas such as adaptive radiotherapy. Conventional outcome models that are based on a simplified understanding of radiobiological effects or e...

Development and Validation of a Deep Learning Model for Predicting Treatment Response in Patients With Newly Diagnosed Epilepsy.

JAMA neurology
IMPORTANCE: Selection of antiseizure medications (ASMs) for epilepsy remains largely a trial-and-error approach. Under this approach, many patients have to endure sequential trials of ineffective treatments until the "right drugs" are prescribed.

Combined docking and machine learning identify key molecular determinants of ligand pharmacological activity on β2 adrenoceptor.

Pharmacology research & perspectives
G protein-coupled receptors (GPCRs) are valuable therapeutic targets for many diseases. A central question of GPCR drug discovery is to understand what determines the agonism or antagonism of ligands that bind them. Ligands exert their action via the...

Artificial intelligence in gastrointestinal endoscopy - Evolution to a new era.

Revista espanola de enfermedades digestivas
Artificial intelligence (AI) systems based on machine learning have evolved in the last few years with an increasing applicability in gastrointestinal endoscopy. Thanks to AI, an image (input) can be transformed into a clinical decision (output). Alt...