AIMC Topic: Machine Learning

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ToxIBTL: prediction of peptide toxicity based on information bottleneck and transfer learning.

Bioinformatics (Oxford, England)
MOTIVATION: Recently, peptides have emerged as a promising class of pharmaceuticals for various diseases treatment poised between traditional small molecule drugs and therapeutic proteins. However, one of the key bottlenecks preventing them from ther...

Molecular Modeling Techniques Applied to the Design of Multitarget Drugs: Methods and Applications.

Current topics in medicinal chemistry
Multifactorial diseases, such as cancer and diabetes present a challenge for the traditional "one-target, one disease" paradigm due to their complex pathogenic mechanisms. Although a combination of drugs can be used, a multitarget drug may be a bette...

Potential for Process Improvement of Clinical Flow Cytometry by Incorporating Real-Time Automated Screening of Data to Expedite Addition of Antibody Panels.

American journal of clinical pathology
OBJECTIVES: We desired an automated approach to expedite ordering additional antibody panels in our clinical flow cytometry lab. This addition could improve turnaround times, decrease time spent revisiting cases, and improve consistency.

Artificial Intelligence in Cardiovascular Medicine: Historical Overview, Current Status, and Future Directions.

Texas Heart Institute journal
Artificial intelligence and machine learning are rapidly gaining popularity in every aspect of our daily lives, and cardiovascular medicine is no exception. Here, we provide physicians with an overview of the past, present, and future of artificial i...

Artificial Intelligence for Education, Proctoring, and Credentialing in Cardiovascular Medicine.

Texas Heart Institute journal
Artificial intelligence and machine learning are rapidly gaining popularity in every aspect of cardiovascular medicine. This review discusses the past, present, and future of artificial intelligence in education, remote proctoring, credentialing, res...

Artificial Intelligence and Machine Learning in Cardiac Electrophysiology.

Texas Heart Institute journal
Cardiac electrophysiology requires the processing of several patient-specific data points in real time to provide an accurate diagnosis and determine an optimal therapy. Expanding beyond the traditional tools that have been used to extract informatio...

Development of a Machine Learning Model Using Limited Features to Predict 6-Month Mortality at Treatment Decision Points for Patients With Advanced Solid Tumors.

JCO clinical cancer informatics
PURPOSE: Patients with advanced solid tumors may receive intensive treatments near the end of life. This study aimed to create a machine learning (ML) model using limited features to predict 6-month mortality at treatment decision points (TDPs).

Data-driven technique for disruption prediction in GOLEM tokamak using stacked ensembles with active learning.

The Review of scientific instruments
In a tokamak, disruption is defined as losing control over a confined plasma resulting in sudden extinction of the plasma current. Machine learning offers potent solutions to classify plasma discharges into disruptive and non-disruptive classes. Evol...

The Analysis of Pain Research through the Lens of Artificial Intelligence and Machine Learning.

Pain physician
BACKGROUND: Traditional pain assessment methods have significant limitations due to the high variability in patient reported pain scores and perception of pain by different individuals. There is a need for generalized and automatic pain detection and...