AIMC Topic: Mania

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Longitudinal brain age in first-episode mania youth treated with lithium or quetiapine.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
It is unclear if lithium and quetiapine have neuroprotective effects, especially in early stages of bipolar and schizoaffective disorders. Here, an age-related multivariate brain structural measure (i.e., brain-PAD) at baseline and changes in respons...

Unlocking treatment success: predicting atypical antipsychotic continuation in youth with mania.

BMC medical informatics and decision making
PURPOSE: This study aimed to create and validate robust machine-learning-based prediction models for antipsychotic drug (risperidone) continuation in children and teenagers suffering from mania over one year and to discover potential variables for cl...