AIMC Topic: Antimanic Agents
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Longitudinal brain age in first-episode mania youth treated with lithium or quetiapine.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
Apr 13, 2025
It is unclear if lithium and quetiapine have neuroprotective effects, especially in early stages of bipolar and schizoaffective disorders. Here, an age-related multivariate brain structural measure (i.e., brain-PAD) at baseline and changes in respons...
Pharmacogenomics and response to lithium in bipolar disorder.
Pharmacogenomics
Feb 25, 2025
AIMS: The present review explores the existing evidence on pharmacogenomic tests for prediction of lithium response in the treatment of bipolar disorder. We focused our research article on reports describing findings from genome-wide association stud...
Predicting maintenance lithium response for bipolar disorder from electronic health records-a retrospective study.
PeerJ
Oct 14, 2024
BACKGROUND: Optimising maintenance drug treatment selection for people with bipolar disorder is challenging. There is some evidence that clinical and demographic features may predict response to lithium. However, attempts to personalise treatment cho...
Prediction of lithium response using clinical data.
Acta psychiatrica Scandinavica
Nov 22, 2019
OBJECTIVE: Promptly establishing maintenance therapy could reduce morbidity and mortality in patients with bipolar disorder. Using a machine learning approach, we sought to evaluate whether lithium responsiveness (LR) is predictable using clinical ma...
What do patients learn about psychotropic medications on the web? A natural language processing study.
Journal of affective disorders
Sep 10, 2019
BACKGROUND: Low rates of medication adherence remain a major challenge across psychiatry. In part, this likely reflects patient concerns about safety and adverse effects, accurate or otherwise. We therefore sought to characterize online information a...
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