Molecular biology of the cell
Dec 1, 2024
The success of artificial intelligence (AI) algorithms in predicting protein structure and more recently, protein interactions, demonstrates the power and potential of machine learning and AI for advancing and accelerating biomedical research. As cel...
Briefings in bioinformatics
Nov 22, 2024
Modelling biological systems depends on the availability of data and components of the system at hand. As our understanding of these systems evolves, the ability to gradually refine models by adding new components of different formalisms covering sto...
Integrative and comparative biology
Nov 21, 2024
Whether walking, running, slithering, or flying, organisms display a remarkable ability to move through complex and uncertain environments. In particular, animals have evolved to cope with a host of uncertainties-both of internal and external origin-...
Ecology letters
Nov 1, 2024
Despite deep learning being state of the art for data-driven model predictions, its application in ecology is currently subject to two important constraints: (i) deep-learning methods are powerful in data-rich regimes, but in ecology data are typical...
Integrative and comparative biology
Sep 27, 2024
Tails play essential roles in functions related to locomotor stability and maneuverability among terrestrial and arboreal animals. In kangaroo rats, bipedal hopping rodents, tails are used as effective inertial appendages for stability in hopping, bu...
Cell
Aug 22, 2024
Comprehensively charting the biologically causal circuits that govern the phenotypic space of human cells has often been viewed as an insurmountable challenge. However, in the last decade, a suite of interleaved experimental and computational technol...
Physical review letters
Jul 26, 2024
Direct mechanical coupling is known to be critical for establishing synchronization among cilia. However, the actual role of the connections is still elusive-partly because controlled experiments in living samples are challenging. Here, we employ an ...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
Musculoskeletal modeling and simulation is often a lengthy and computationally expensive process, particularly when developing and using personalized models. We present a deep learning-based adaptive surrogate model for lateral pinch, which accepts b...
Clinical and translational science
May 1, 2024
Accurate prediction of a new compound's pharmacokinetic (PK) profile is pivotal for the success of drug discovery programs. An initial assessment of PK in preclinical species and humans is typically performed through allometric scaling and mathematic...
Artificial life
May 1, 2024
Biological agents have bodies that are composed mostly of soft tissue. Researchers have resorted to soft bodies to investigate Artificial Life (ALife)-related questions; similarly, a new era of soft-bodied robots has just begun. Nevertheless, because...