AIMC Topic: Lipoproteins

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Lipoproteins and metabolites in diagnosing and predicting Alzheimer's disease using machine learning.

Lipids in health and disease May 21, 2024
BACKGROUND: Alzheimer's disease (AD) is a chronic neurodegenerative disorder that poses a substantial economic burden. The Random forest algorithm is effective in predicting AD; however, the key factors influencing AD onset remain unclear. This study...
Machine Learning Algorithms Biomarkers Female Humans Alzheimer Disease Aged Aged, 80 and over Male Lipoproteins
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TRENDS IN CHOLESTEROL AND LIPOPROTEINS ARE ASSOCIATED WITH ACUTE RESPIRATORY DISTRESS SYNDROME INCIDENCE AND DEATH AMONG SEPSIS PATIENTS.

Shock (Augusta, Ga.) Dec 28, 2023
Objective: Compare changes in cholesterol and lipoprotein levels occurring in septic patients with and without acute respiratory distress syndrome (ARDS) and by survivorship. Methods: We reanalyzed data from prospective sepsis studies. Cholesterol an...
Cholesterol, LDL Cholesterol Incidence Respiratory Distress Syndrome Lipoproteins Apolipoprotein A-I Humans Prospective Studies Sepsis
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The effect of fasting status on lipids, lipoproteins, and inflammatory biomarkers assessed after hospitalization for an acute coronary syndrome: Insights from PROVE IT-TIMI 22.

Clinical cardiology Dec 28, 2017
BACKGROUND: For decades, fasting for 8 to 12 hours has been recommended for measurement of lipid profiles. The effect of fasting on low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG) has been described in healthy cohorts and those wit...
Pravastatin Immunoturbidimetry Lipoproteins Prognosis Acute Coronary Syndrome Retrospective Studies Atorvastatin Female Inflammation Hospitalization Humans Follow-Up Studies Male Biomarkers Middle Aged Dose-Response Relationship, Drug Fasting Lipids Colorimetry
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Unveiling lipoprotein subfractions signature in high-FNPO PCOS: implications for PCOM diagnosis and risk assessment using advanced machine learning models.

BMC medicine May 19, 2025
BACKGROUND: Polycystic ovary syndrome (PCOS) is a common reproductive and metabolic disorder in the reproductive-age women. The international evidence-based guideline for the assessment and management of PCOS 2023 now suggests raising the follicle nu...
Humans Machine Learning Biomarkers Case-Control Studies Lipoproteins Polycystic Ovary Syndrome Ovary Female Young Adult Adult Risk Assessment
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Machine Learning Reveals the Contribution of Lipoproteins to Liver Triglyceride Content and Inflammation.

The Journal of clinical endocrinology and metabolism Dec 18, 2024
CONTEXT: Metabolic dysfunction-associated steatotic liver disease (MASLD) is currently the most common chronic liver disease worldwide and is strongly associated with metabolic comorbidities, including dyslipidemia.
Hypertriglyceridemia Lipoproteins United Kingdom Aged Hypercholesterolemia Adult Triglycerides Male Humans Middle Aged Prevalence Machine Learning Fatty Liver Female Inflammation Liver
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Incremental modelling and analysis of biological systems with fuzzy hybrid Petri nets.

Briefings in bioinformatics Nov 22, 2024
Modelling biological systems depends on the availability of data and components of the system at hand. As our understanding of these systems evolves, the ability to gradually refine models by adding new components of different formalisms covering sto...
Humans Algorithms Fuzzy Logic Hypercholesterolemia Lipoproteins Cholesterol Models, Biological
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Elevated tissue factor pathway inhibitor is associated with intracerebral haemorrhage of unknown cause in young adults.

Neurologia i neurochirurgia polska Jan 1, 2024
CLINICAL RATIONALE FOR STUDY: We have reported that intracerebral haemorrhage (ICH) of unknown cause at a young age is associated with lower prothrombin and factor VII and higher antithrombin activity, along with the formation of looser fibrin networ...
Lipoproteins Adult Humans Male Female Middle Aged Young Adult Cerebral Hemorrhage
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Verification and comparison of three prediction models of ischemic stroke in young adults based on the back propagation neural networks.

Medicine Mar 19, 2021
This work aims to explore risk factors for ischemic stroke in young adults and analyze the Traditional Vascular Risk Factors Model based on age, hypertension, diabetes, smoking history, and drinking history. Further, the Lipid Metabolism Model was an...
Smoking Alcohol Drinking Clinical Decision Rules Hypertension Kidney Function Tests Age Factors Lipoproteins Predictive Value of Tests Ischemic Stroke Factor Analysis, Statistical Area Under Curve Risk Assessment Adolescent ROC Curve Diabetes Mellitus, Type 2 Adult Humans Male Neural Networks, Computer Middle Aged Acute Kidney Injury Female Risk Factors Young Adult
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Association of ATP-Binding Cassette Transporter (ABC) Gene Polymorphisms with Viral Load in Patients with Genotype 1 Hepatitis C Virus Infection.

Clinical laboratory Sep 1, 2016
BACKGROUND: ATP-binding cassette transporters (ABC) gene polymorphisms are associated with various biological functions, including hepatitis C virus (HCV) infection. This study aims to explore the impact of ABC transporters polymorphisms on HCV viral...
Male Middle Aged Viral Load Polymorphism, Single Nucleotide Genotype Lipoproteins Interleukins Neoplasm Proteins Humans ATP Binding Cassette Transporter, Subfamily G, Member 2 Female ATP Binding Cassette Transporter, Subfamily G, Member 5 ATP-Binding Cassette Transporters ATP Binding Cassette Transporter, Subfamily B, Member 1 ATP Binding Cassette Transporter 1 Hepacivirus ATP Binding Cassette Transporter, Subfamily B Hepatitis C, Chronic ATP Binding Cassette Transporter, Subfamily B, Member 11 Gene Frequency
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