AIMC Topic: Chlamydomonas reinhardtii
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Dual-Stage Propulsion Strategy for Microalgae-Based Biohybrid Microrobots.
ACS applied materials & interfaces
Jun 3, 2025
Biohybrid microrobots, based on swimming microalgae, offer outstanding self-propulsion and functionalization capabilities, making them promising platforms for cargo loading and delivery. However, current technologies predominantly focus on in vitro n...
Deep learning improves macromolecule identification in 3D cellular cryo-electron tomograms.
Nature methods
Oct 21, 2021
Cryogenic electron tomography (cryo-ET) visualizes the 3D spatial distribution of macromolecules at nanometer resolution inside native cells. However, automated identification of macromolecules inside cellular tomograms is challenged by noise and rec...
A deep learning based approach for prediction of Chlamydomonas reinhardtii phosphorylation sites.
Scientific reports
Jun 15, 2021
Protein phosphorylation, which is one of the most important post-translational modifications (PTMs), is involved in regulating myriad cellular processes. Herein, we present a novel deep learning based approach for organism-specific protein phosphoryl...
Multiview learning for understanding functional multiomics.
PLoS computational biology
Apr 2, 2020
The molecular mechanisms and functions in complex biological systems currently remain elusive. Recent high-throughput techniques, such as next-generation sequencing, have generated a wide variety of multiomics datasets that enable the identification ...
Detection of DNA base modifications by deep recurrent neural network on Oxford Nanopore sequencing data.
Nature communications
Jun 4, 2019
DNA base modifications, such as C5-methylcytosine (5mC) and N6-methyldeoxyadenosine (6mA), are important types of epigenetic regulations. Short-read bisulfite sequencing and long-read PacBio sequencing have inherent limitations to detect DNA modifica...
High-Throughput Robotically Assisted Isolation of Temperature-sensitive Lethal Mutants in Chlamydomonas reinhardtii.
Journal of visualized experiments : JoVE
Dec 5, 2016
Systematic identification and characterization of genetic perturbations have proven useful to decipher gene function and cellular pathways. However, the conventional approaches of permanent gene deletion cannot be applied to essential genes. We have ...
Biomimetic Synchronization in Biciliated Robots.
Physical review letters
Jul 26, 2024
Direct mechanical coupling is known to be critical for establishing synchronization among cilia. However, the actual role of the connections is still elusive-partly because controlled experiments in living samples are challenging. Here, we employ an ...
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