AIMC Topic: Models, Statistical

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A new modeling approach for quantifying expert opinion in the drug discovery process.

Statistics in medicine
Expert opinion plays an important role when choosing clusters of chemical compounds for further investigation. Often, the process by which the clusters are assigned to the experts for evaluation, the so-called selection process, and the qualitative r...

BgN-Score and BsN-Score: bagging and boosting based ensemble neural networks scoring functions for accurate binding affinity prediction of protein-ligand complexes.

BMC bioinformatics
BACKGROUND: Accurately predicting the binding affinities of large sets of protein-ligand complexes is a key challenge in computational biomolecular science, with applications in drug discovery, chemical biology, and structural biology. Since a scorin...

A Recurrent Probabilistic Neural Network with Dimensionality Reduction Based on Time-series Discriminant Component Analysis.

IEEE transactions on neural networks and learning systems
This paper proposes a probabilistic neural network (NN) developed on the basis of time-series discriminant component analysis (TSDCA) that can be used to classify high-dimensional time-series patterns. TSDCA involves the compression of high-dimension...

Local Rademacher Complexity: sharper risk bounds with and without unlabeled samples.

Neural networks : the official journal of the International Neural Network Society
We derive in this paper a new Local Rademacher Complexity risk bound on the generalization ability of a model, which is able to take advantage of the availability of unlabeled samples. Moreover, this new bound improves state-of-the-art results even w...

Delay-dependent finite-time boundedness of a class of Markovian switching neural networks with time-varying delays.

ISA transactions
In this paper, a novel method is developed for delay-dependent finite-time boundedness of a class of Markovian switching neural networks with time-varying delays. New sufficient condition for stochastic boundness of Markovian jumping neural networks ...

Improving forecasting accuracy of medium and long-term runoff using artificial neural network based on EEMD decomposition.

Environmental research
Hydrological time series forecasting is one of the most important applications in modern hydrology, especially for the effective reservoir management. In this research, an artificial neural network (ANN) model coupled with the ensemble empirical mode...

Huffman and linear scanning methods with statistical language models.

Augmentative and alternative communication (Baltimore, Md. : 1985)
Current scanning access methods for text generation in AAC devices are limited to relatively few options, most notably row/column variations within a matrix. We present Huffman scanning, a new method for applying statistical language models to binary...

Domain adaption of parsing for operative notes.

Journal of biomedical informatics
BACKGROUND: Full syntactic parsing of clinical text as a part of clinical natural language processing (NLP) is critical for a wide range of applications. Several robust syntactic parsers are publicly available to produce linguistic representations fo...

Structured patch model for a unified automatic and interactive segmentation framework.

Medical image analysis
We present a novel interactive segmentation framework incorporating a priori knowledge learned from training data. The knowledge is learned as a structured patch model (StPM) comprising sets of corresponding local patch priors and their pairwise spat...