Monoacylglycerol Lipases

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Endocannabinoid degradation inhibitors ameliorate neuronal and synaptic alterations following traumatic brain injury.

Journal of neurophysiology Jan 8, 2020
Our previous work showed that lateral fluid percussion injury to the sensorimotor cortex (SMC) of anesthetized rats increased neuronal synaptic hyperexcitability in layer 5 (L5) neurons in ex vivo brain slices 10 days postinjury. Furthermore, endocan...
Machine Learning Animals Male Rats, Wistar Rats Brain Injuries, Traumatic Piperazines Piperidines Enzyme Inhibitors Carbamates Amidohydrolases Succinimides Benzamides Pyramidal Cells Electrophysiological Phenomena Excitatory Postsynaptic Potentials Sensorimotor Cortex Endocannabinoids Benzodioxoles Monoacylglycerol Lipases
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