AIMC Topic: Excitatory Postsynaptic Potentials

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A novel machine learning-based approach for the detection and analysis of spontaneous synaptic currents.

PloS one Sep 19, 2022
Spontaneous synaptic activity is a hallmark of biological neural networks. A thorough description of these synaptic signals is essential for understanding neurotransmitter release and the generation of a postsynaptic response. However, the complexity...
Humans Mice Synaptic Transmission Excitatory Postsynaptic Potentials Neurotransmitter Agents Machine Learning Algorithms Animals
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Long-Tailed Characteristic of Spiking Pattern Alternation Induced by Log-Normal Excitatory Synaptic Distribution.

IEEE transactions on neural networks and learning systems Aug 3, 2021
Studies of structural connectivity at the synaptic level show that in synaptic connections of the cerebral cortex, the excitatory postsynaptic potential (EPSP) in most synapses exhibits sub-mV values, while a small number of synapses exhibit large EP...
Synaptic Transmission Excitatory Postsynaptic Potentials Cerebral Cortex Nerve Net Entropy Nonlinear Dynamics Algorithms Synapses Models, Neurological Humans Neural Networks, Computer
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Modulation of the dynamics of cerebellar Purkinje cells through the interaction of excitatory and inhibitory feedforward pathways.

PLoS computational biology Feb 10, 2021
The dynamics of cerebellar neuronal networks is controlled by the underlying building blocks of neurons and synapses between them. For which, the computation of Purkinje cells (PCs), the only output cells of the cerebellar cortex, is implemented thro...
Neural Networks, Computer Computer Simulation Animals Humans Action Potentials Neurons Cerebellum Synapses Signal Transduction Neuronal Plasticity Models, Neurological Cerebellar Cortex Interneurons Purkinje Cells Excitatory Postsynaptic Potentials Neural Pathways Normal Distribution Synaptic Transmission
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Electret-Based Organic Synaptic Transistor for Neuromorphic Computing.

ACS applied materials & interfaces Mar 18, 2020
Neuromorphic computing inspired by the neural systems in human brain will overcome the issue of independent information processing and storage. An artificial synaptic device as a basic unit of a neuromorphic computing system can perform signal proces...
Signal-To-Noise Ratio Humans Polyvinyls Excitatory Postsynaptic Potentials Neural Networks, Computer Synapses Transistors, Electronic
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Endocannabinoid degradation inhibitors ameliorate neuronal and synaptic alterations following traumatic brain injury.

Journal of neurophysiology Jan 8, 2020
Our previous work showed that lateral fluid percussion injury to the sensorimotor cortex (SMC) of anesthetized rats increased neuronal synaptic hyperexcitability in layer 5 (L5) neurons in ex vivo brain slices 10 days postinjury. Furthermore, endocan...
Male Rats, Wistar Rats Brain Injuries, Traumatic Piperazines Piperidines Machine Learning Animals Electrophysiological Phenomena Succinimides Excitatory Postsynaptic Potentials Enzyme Inhibitors Endocannabinoids Benzamides Monoacylglycerol Lipases Sensorimotor Cortex Carbamates Pyramidal Cells Benzodioxoles Amidohydrolases
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Dendritic computations captured by an effective point neuron model.

Proceedings of the National Academy of Sciences of the United States of America Jul 10, 2019
Complex dendrites in general present formidable challenges to understanding neuronal information processing. To circumvent the difficulty, a prevalent viewpoint simplifies the neuronal morphology as a point representing the soma, and the excitatory a...
Voltage-Gated Sodium Channels CA1 Region, Hippocampal Potassium Channels, Voltage-Gated Excitatory Postsynaptic Potentials Rats Neural Networks, Computer Rats, Sprague-Dawley Neurons Animals Synapses
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Organic Synapses for Neuromorphic Electronics: From Brain-Inspired Computing to Sensorimotor Nervetronics.

Accounts of chemical research Mar 21, 2019
Living organisms have a long evolutionary history that has provided them with functions and structures that enable them to survive in their environment. The goal of biomimetic technology is to emulate these traits of living things. Research in bioins...
Electronics Biomimetics Synapses Humans Brain Excitatory Postsynaptic Potentials Robotics
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Synaptic Metaplasticity Realized in Oxide Memristive Devices.

Advanced materials (Deerfield Beach, Fla.) Nov 17, 2015
Metaplasticity, a higher order of synaptic plasticity, as well as a key issue in neuroscience, is realized with artificial synapses based on a WO3 thin film, and the activity-dependent metaplastic responses of the artificial synapses, such as spike-t...
Biomimetic Materials Microscopy, Electron, Transmission Optical Imaging Electrical Equipment and Supplies Time Oxides Neural Networks, Computer Excitatory Postsynaptic Potentials Equipment Design Neuronal Plasticity Synapses Action Potentials
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Distinct subtypes of inhibitory interneurons differentially promote the propagation of rate and temporal codes in the feedforward neural network.

Chaos (Woodbury, N.Y.) May 1, 2020
Sensory information is believed to be encoded in neuronal spikes using two different neural codes, the rate code (spike firing rate) and the temporal code (precisely-timed spikes). Since the sensory cortex has a highly hierarchical feedforward struct...
Excitatory Postsynaptic Potentials Parvalbumins Neural Networks, Computer Action Potentials Neurons Perception Interneurons Pyramidal Cells
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