AIMC Topic: Peptides, Cyclic
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MuCoCP: a priori chemical knowledge-based multimodal contrastive learning pre-trained neural network for the prediction of cyclic peptide membrane penetration ability.
Bioinformatics (Oxford, England)
Aug 2, 2024
MOTIVATION: There has been a burgeoning interest in cyclic peptide therapeutics due to their various outstanding advantages and strong potential for drug formation. However, it is undoubtedly costly and inefficient to use traditional wet lab methods ...
CyclicPepedia: a knowledge base of natural and synthetic cyclic peptides.
Briefings in bioinformatics
Mar 27, 2024
Cyclic peptides offer a range of notable advantages, including potent antibacterial properties, high binding affinity and specificity to target molecules, and minimal toxicity, making them highly promising candidates for drug development. However, a ...
Plasma protein binding prediction focusing on residue-level features and circularity of cyclic peptides by deep learning.
Bioinformatics (Oxford, England)
Jan 27, 2022
MOTIVATION: In recent years, cyclic peptide drugs have been receiving increasing attention because they can target proteins that are difficult to be tackled by conventional small-molecule drugs or antibody drugs. Plasma protein binding rate (%PPB) is...
Bacillus methylotrophicus ASWU-C2, a strain inhabiting hot desert soil, a new source for antibacterial bacillopyrone, pyrophen, and cyclopeptides.
Zeitschrift fur Naturforschung. C, Journal of biosciences
Dec 19, 2018
A strain of Bacillus methylotrophicus was isolated from a soil sample collected in Aswan eastern desert, which is known for its extremely arid climate. After fermentation of the strain in liquid culture and subsequent extraction, a bioassay-guided is...
[Identification of ustiloxins in false smut balls of rice based on high performance liquid chromatography-high resolution mass spectrometry].
Se pu = Chinese journal of chromatography
Oct 1, 2015
A sensitive method was developed for the simultaneous identification of five ustiloxins in the false smut balls of rice by high performance liquid chromatography-linear ion trap/orbitrap high resolution mass spectrometry (HPLC-LTQ/Orbitrap MS). The s...
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