AIMC Topic: Peptides
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An introduction to deep learning on biological sequence data: examples and solutions.
Bioinformatics (Oxford, England)
Nov 15, 2017
MOTIVATION: Deep neural network architectures such as convolutional and long short-term memory networks have become increasingly popular as machine learning tools during the recent years. The availability of greater computational resources, more data...
modlAMP: Python for antimicrobial peptides.
Bioinformatics (Oxford, England)
Sep 1, 2017
SUMMARY: We have implemented the lecular esign aboratory's nti icrobial eptides package ( ), a Python-based software package for the design, classification and visual representation of peptide data. modlAMP offers functions for molecular descriptor c...
HLA class I binding prediction via convolutional neural networks.
Bioinformatics (Oxford, England)
Sep 1, 2017
MOTIVATION: Many biological processes are governed by protein-ligand interactions. One such example is the recognition of self and non-self cells by the immune system. This immune response process is regulated by the major histocompatibility complex ...
NNAlign: a platform to construct and evaluate artificial neural network models of receptor-ligand interactions.
Nucleic acids research
Jul 3, 2017
Peptides are extensively used to characterize functional or (linear) structural aspects of receptor-ligand interactions in biological systems, e.g. SH2, SH3, PDZ peptide-recognition domains, the MHC membrane receptors and enzymes such as kinases and ...
Internet
Forkhead Transcription Factors
Amino Acid Sequence
Protein Binding
Databases, Protein
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Trans-Activators
Sequence Alignment
HLA-A1 Antigen
Ligands
Cell Cycle Proteins
Binding Sites
Humans
Neural Networks, Computer
Software
Algorithms
Peptides
HLA-B7 Antigen
HLA-B8 Antigen
HLA-DRB1 Chains
[Clinical analysis of Cervus and Cucumis Polypeptide injection based on real world hospital information system].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Nov 1, 2016
To analyze the clinical application of Cervus and Cucumis Polypeptide injection in the real world, in order to define the characteristics of clinical drug use and correlation, and provide reference for risk management and further study for Cervus and...
An Evaluation on Different Machine Learning Algorithms for Classification and Prediction of Antifungal Peptides.
Medicinal chemistry (Shariqah (United Arab Emirates))
Jan 1, 2016
BACKGROUND: Fungi are an emerging threat in medicine and agriculture and current therapeutics have proved to be insufficient and toxic. This has led to an increased interest in peptide-based therapeutics, especially antifungal peptides (AFPs), being ...
[Enhancement of Coprinus cinereus peroxidase in Pichia pastoris by co-expression chaperone PDI and Ero1].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Dec 1, 2015
The 1,095 bp gene encoding peroxidase from Coprinus cinereus was synthesized and integrated into the genome of Pichia pastoris with a highly inducible alcohol oxidase. The recombinant CiP (rCiP) fused with the a-mating factor per-pro leader sequence ...
[Collagen quantitation by detection of marker peptides with HPLC-MS].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Nov 1, 2015
A method for quantitation of collagen was established by detecting marker peptide with high performance liquid chromatography-mass spectrometry (HPLC-MS). Theoretical marker peptides were selected by sequence comparison. Bovine collagen type I was di...
[Bactericidal Activity of Constructed Recombinant Fusion Protein Pheromonicin-CT].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
Nov 1, 2015
OBJECTIVE: To construct engineering peptide pheromonicin-Clostrzaum tretant krn-ui), and to test its bactericidal activity.
AVP-IC50 Pred: Multiple machine learning techniques-based prediction of peptide antiviral activity in terms of half maximal inhibitory concentration (IC50).
Biopolymers
Nov 1, 2015
Peptide-based antiviral therapeutics has gradually paved their way into mainstream drug discovery research. Experimental determination of peptides' antiviral activity as expressed by their IC50 values involves a lot of effort. Therefore, we have deve...
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