AIMC Topic: Phylogeny

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PTGAC Model: A machine learning approach for constructing phylogenetic tree to compare protein sequences.

Journal of bioinformatics and computational biology
This work proposes a machine learning-based phylogenetic tree generation model based on agglomerative clustering (PTGAC) that compares protein sequences considering all known chemical properties of amino acids. The proposed model can serve as a suita...

Machine learning classifiers predict key genomic and evolutionary traits across the kingdoms of life.

Scientific reports
In this study, we investigate how an organism's codon usage bias can serve as a predictor and classifier of various genomic and evolutionary traits across the domains of life. We perform secondary analysis of existing genetic datasets to build severa...

Predicting Antigenic Distance from Genetic Data for PRRSV-Type 1: Applications of Machine Learning.

Microbiology spectrum
The control of porcine reproductive and respiratory syndrome (PRRS) remains a significant challenge due to the genetic and antigenic variability of the causative virus (PRRSV). Predominantly, PRRSV management includes using vaccines and live virus in...

The impacts of fine-tuning, phylogenetic distance, and sample size on big-data bioacoustics.

PloS one
Vocalizations in animals, particularly birds, are critically important behaviors that influence their reproductive fitness. While recordings of bioacoustic data have been captured and stored in collections for decades, the automated extraction of dat...

A deep learning approach to real-time HIV outbreak detection using genetic data.

PLoS computational biology
Pathogen genomic sequence data are increasingly made available for epidemiological monitoring. A main interest is to identify and assess the potential of infectious disease outbreaks. While popular methods to analyze sequence data often involve phylo...

Quartet Based Gene Tree Imputation Using Deep Learning Improves Phylogenomic Analyses Despite Missing Data.

Journal of computational biology : a journal of computational molecular cell biology
Species tree estimation is frequently based on phylogenomic approaches that use multiple genes from throughout the genome. However, for a combination of reasons (ranging from sampling biases to more biological causes, as in gene birth and loss), gene...

The origin and evolution of open habitats in North America inferred by Bayesian deep learning models.

Nature communications
Some of the most extensive terrestrial biomes today consist of open vegetation, including temperate grasslands and tropical savannas. These biomes originated relatively recently in Earth's history, likely replacing forested habitats in the second hal...

New feature extraction from phylogenetic profiles improved the performance of pathogen-host interactions.

Frontiers in cellular and infection microbiology
MOTIVATION: The understanding of pathogen-host interactions (PHIs) is essential and challenging research because this potentially provides the mechanism of molecular interactions between different organisms. The experimental exploration of PHI is tim...

bHLHDB: A next generation database of basic helix loop helix transcription factors based on deep learning model.

Journal of bioinformatics and computational biology
The basic helix loop helix (bHLH) superfamily is a large and diverse protein family that plays a role in various vital functions in nearly all animals and plants. The bHLH proteins form one of the largest families of transcription factors found in pl...

Invariant transformers of Robinson and Foulds distance matrices for Convolutional Neural Network.

Journal of bioinformatics and computational biology
The evolutionary histories of genes are susceptible of differing greatly from each other which could be explained by evolutionary variations in horizontal gene transfers or biological recombinations. A phylogenetic tree would therefore represent the ...