AIMC Topic: Plasmodium

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An Effective Convolutional Neural Network for Classifying Red Blood Cells in Malaria Diseases.

Interdisciplinary sciences, computational life sciences May 11, 2020
Malaria is one of the epidemics that can cause human death. Accurate and rapid diagnosis of malaria is important for treatment. Due to the limited number of data and human factors, the prediction performance and reliability of traditional classificat...
Humans Neural Networks, Computer Reproducibility of Results Deep Learning Malaria Models, Biological Erythrocytes Plasmodium
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Age grading An. gambiae and An. arabiensis using near infrared spectra and artificial neural networks.

PloS one Aug 14, 2019
BACKGROUND: Near infrared spectroscopy (NIRS) is currently complementing techniques to age-grade mosquitoes. NIRS classifies lab-reared and semi-field raised mosquitoes into < or ≥ 7 days old with an average accuracy of 80%, achieved by training a re...
Neural Networks, Computer Female Animals Male Aging Spectroscopy, Near-Infrared Models, Statistical Malaria Population Density Plasmodium Anopheles
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CAPi: Computational Model for Apicoplast Inhibitors Prediction Against Plasmodium Parasite.

Current computer-aided drug design Nov 10, 2017
BACKGROUND: Discovery of apicoplast as a drug target offers a new direction in the development of novel anti-malarial compounds, especially against the drug-resistant strains. Drugs such as azithromycin were reported to block the apicoplast developme...
Humans Machine Learning Software Algorithms Computer Simulation Drug Discovery Malaria Models, Biological Antimalarials High-Throughput Screening Assays Databases, Pharmaceutical Plasmodium
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Artificial Neural Network Analysis of Pharmacokinetic and Toxicity Properties of Lead Molecules for Dengue Fever, Tuberculosis and Malaria.

Current computer-aided drug design Jan 1, 2016
Poor pharmacokinetic and toxicity profiles are major reasons for the low rate of advancing lead drug candidates into efficacy studies. The In-silico prediction of primary pharmacokinetic and toxicity properties in the drug discovery and development p...
Humans Neural Networks, Computer Anti-Infective Agents Computer Simulation Animals Computer-Aided Design Drug Design Mice Malaria Tuberculosis Dengue Virus Mycobacterium Dengue Ether-A-Go-Go Potassium Channels Plasmodium
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