AIMC Topic: Prokaryotic Cells

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Deepdefense: annotation of immune systems in prokaryotes using deep learning.

GigaScience Jan 2, 2024
BACKGROUND: Due to a constant evolutionary arms race, archaea and bacteria have evolved an abundance and diversity of immune responses to protect themselves against phages. Since the discovery and application of CRISPR-Cas adaptive immune systems, nu...
Neural Networks, Computer Algorithms Deep Learning Bacteria Computational Biology Immune System Molecular Sequence Annotation Archaea Prokaryotic Cells
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IPEV: identification of prokaryotic and eukaryotic virus-derived sequences in virome using deep learning.

GigaScience Jan 2, 2024
BACKGROUND: The virome obtained through virus-like particle enrichment contains a mixture of prokaryotic and eukaryotic virus-derived fragments. Accurate identification and classification of these elements are crucial to understanding their roles and...
Humans Software Deep Learning Computational Biology Genome, Viral Viruses Eukaryota Prokaryotic Cells Virome
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Elucidating the functional roles of prokaryotic proteins using big data and artificial intelligence.

FEMS microbiology reviews Jan 16, 2023
Annotating protein sequences according to their biological functions is one of the key steps in understanding microbial diversity, metabolic potentials, and evolutionary histories. However, even in the best-studied prokaryotic genomes, not all protei...
Artificial Intelligence Machine Learning Algorithms Molecular Sequence Annotation Prokaryotic Cells
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NetGO: improving large-scale protein function prediction with massive network information.

Nucleic acids research Jul 2, 2019
Automated function prediction (AFP) of proteins is of great significance in biology. AFP can be regarded as a problem of the large-scale multi-label classification where a protein can be associated with multiple gene ontology terms as its labels. Bas...
Humans Machine Learning Software Animals Computational Biology Proteins Databases, Protein Structure-Activity Relationship Models, Molecular Internet Benchmarking Plants Amino Acid Sequence Molecular Sequence Annotation Gene Ontology Protein Interaction Mapping Sequence Alignment Sequence Homology, Amino Acid Sequence Analysis, Protein Prokaryotic Cells
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