AIMC Topic: Quantum Dots

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Investigation of the effects of carbon-based nanomaterials on A53T alpha-synuclein aggregation using a whole-cell recombinant biosensor.

International journal of nanomedicine
The aggregation of alpha-synuclein (αS), natively unstructured presynaptic protein, is a crucial factor leading to the pathogenesis of Parkinson's disease (PD) and other related disorders. Recent studies have shown prefibrillar and oligomeric interme...

Aptamer based fluorometric β-lactoglobulin assay based on the use of magnetic nanoparticles and carbon dots.

Mikrochimica acta
The authors describe a fluorometric aptamer based assay for detecting β-lactoglobulin by using carbon dots (C-dots) as a signal indicator. The aptamer was immoblized on magnetite (FeO) nanoparticles (MNPs), and the C-dots served as a label for the co...

Modification-free carbon dots as turn-on fluorescence probe for detection of organophosphorus pesticides.

Food chemistry
It is important to detect pesticides residues due to the concern over food safety. In this work, the burning ash of waste paper was used as carbon source to synthesize carbon dots (C-dots). The fluorescence of obtained C-dots could been turn off by F...

Fluorescence resonance energy transfer aptasensor between nanoceria and graphene quantum dots for the determination of ochratoxin A.

Analytica chimica acta
In the present work, colloidal cerium oxide nanoparticles (nanoceria) and graphene quantum dots (GQDs) were firstly synthesized by sol-gel method and pyrolysis respectively, which all have a uniform nano-size and significant fluorescence emission. Du...

A neural controller for online laser power adjustment during the heat therapy process in the presence of nanoparticles.

Australasian physical & engineering sciences in medicine
The present research evaluated the efficiency of a control approach to control the temperature of a breast tumor mass in the presence of nanoparticles exposed to laser radiation. However, if the radiation is carried out in open loop manner it may res...

Use of quantum dot beads-labeled monoclonal antibody to improve the sensitivity of a quantitative and simultaneous immunochromatographic assay for neuron specific enolase and carcinoembryonic antigen.

Talanta
Detection of multiplex tumor markers was of great importance for cancer diagnosis. Immunochromatographic test strip (ICTS) was the most frequently-used point-of-care detection means. Herein, a convenient and fast method for simultaneous quantitative ...

Optimization of an Anti-poly(ethylene glycol) (anti-PEG) Cell-Based Capture System To Quantify PEG and PEGylated Molecules.

Analytical chemistry
Sensitive determination of the pharmacokinetics of PEGylated molecules can accelerate the process of drug development. Here, we combined different anti-PEG Fab expressing 293T cells as capture cells (293T/3.3, 293T/6.3, and 293T/15-2b cells) with fou...

A "Turn-on-off-on" fluorescence switch based on quantum dots and gold nanoparticles for discriminative detection of ovotransferrin.

Talanta
A novel strategy for ovotransferrin (OVT) detection by tracing the "on-off-on" fluorescence signals of quantum dots (QDs) and gold nanoparticles (AuNPs) utilizing fluorescence measurements were established in this article. The immune interaction betw...

Label-free and dynamic evaluation of cell-surface epidermal growth factor receptor expression via an electrochemiluminescence cytosensor.

Talanta
A label-free electrochemiluminescence (ECL) cytosensor was developed for dynamically evaluating of epidermal growth factor receptor (EGFR) expression on MCF-7 cancer cells based on the specific recognition of epidermal growth factor (EGF) with its re...

Portable and intelligent ratio fluorometry and colorimetry for dual-mode detection of dopamine based on B, N-codoped carbon dots and machine learning.

Talanta
A dual-mode approach was developed for dopamine (DA) assay based on boron (B) and nitrogen (N) co-doped carbon dots (B, N-CDs). This platform enabled highly sensitive and specific detection of DA in biological samples through collaborative ratio fluo...