Photodynamic therapy (PDT) is an emerging approach for tumor treatment, valued for its noninvasive and stimuli-responsive properties. However, its therapeutic efficacy is often constrained by unintended damage to healthy tissues, largely due to the s...
The journal of physical chemistry letters
Nov 30, 2025
This study centers on corrole, an emerging photosensitizer with great application potential, and innovatively develops an intelligent machine learning-based screening strategy. Through integrating molecular descriptor generation, feature engineering,...
Hematoporphyrin monomethyl ether-photodynamic therapy (HMME-PDT) is a safe and effective treatment for port-wine stain (PWS). Comprehensive methods for predicting HMME-PDT efficacy based on clinical factors are lacking. This study aims to develop and...
Multimodal phototheranostics utilizing single molecules offer a "one-and-done" approach, presenting a convenient and effective strategy for cancer therapy. However, therapies based on conventional photosensitizers often suffer from limitations such a...
The combination of Ca overload and reactive oxygen species (ROS) production for cancer therapy offers a superior solution to the lack of specificity in traditional antitumor strategies. However, current therapeutic platforms for this strategy are pri...
According to the World Health Organization (WHO) and the International Agency for Research on Cancer (IARC), the number of cancer cases and deaths worldwide is predicted to nearly double by 2030, reaching 21.7 million cases and 13 million fatalities....
Photodiagnosis and photodynamic therapy
Jun 6, 2024
BACKGROUND: The treatment of oral leukoplakia (OLK) with aminolaevulinic acid photodynamic therapy (ALA-PDT) is widespread. Nonetheless, there is variation in efficacy. Therefore, this study constructed a model for predicting the short-term efficacy ...
Photodiagnosis and photodynamic therapy
Nov 9, 2023
BACKGROUND: To quantitatively evaluate the effectiveness of the Noise2Noise (N2N) model, a deep learning (DL)-based noise reduction algorithm, on enhanced depth imaging-optical coherence tomography (EDI-OCT) images with different noise levels.
Photodiagnosis and photodynamic therapy
Nov 4, 2023
OBJECTIVE: Rheumatoid arthritis and Ankylosing spondylitis are two common autoimmune inflammatory rheumatic diseases that negatively affect activities of daily living and can lead to structural and functional disability, reduced quality of life. Here...
Photodiagnosis and photodynamic therapy
Sep 22, 2023
Strabismus is a condition in which one or both eyes do not work in parallel or in harmony. People with strabismus have one eye looking straight ahead while the other eye looks inwards, outwards, upwards or downwards. This condition can affect both ey...
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