In cancer combination therapy, micro-robot systems that integrate multiple therapeutic functions have emerged as a key direction for overcoming the limitations of traditional treatments. This study proposes a magnetic thermosensitive hydrogel capsule...
International journal of pharmaceutics
Nov 4, 2025
Liposomes have transformed drug delivery by enhancing the solubility, stability, and bioavailability of therapeutic agents, driving widespread clinical adoption and contributing to a rapidly expanding multi-billion-dollar market. However, despite the...
AlphaFold, a deep learning-based platform widely used to predict protein and peptide structures, was employed in this study to model the self-assembling peptide RFC, which demonstrated a stable α-helical structure with high confidence. This structura...
International journal of pharmaceutics
Aug 28, 2025
Label-free characterization of nanoscale drug delivery systems remains a critical challenge in pharmaceutical research. Traditional analytical methods, such as cryo-electron microscopy, are labor-intensive, low-throughput, and often require labeling,...
The performance of electrochemical sensors is influenced by various factors. To enhance the effectiveness of these sensors, it is crucial to find the right balance among these factors. Researchers and engineers continually explore innovative approach...
OBJECTIVE: Quantitative systems pharmacology (QSP) is widely used to assess drug effects and toxicity before the drug goes to clinical trial. However, significant manual distillation of the literature is needed in order to construct a QSP model. Para...
This work developed a cell damage recognition method based on single-cell arrays using an artificial intelligence tool. The method uses micropatterns (single-cell micropatches and microwells) to isolate each cell in an ordered array to minimize cell ...
Medical & biological engineering & computing
Jan 20, 2025
Doxorubicin (DOXO) is a primary treatment for breast cancer but can cause cardiotoxicity in over 25% of patients within the first year post-chemotherapy. Recognizing at-risk patients before DOXO initiation offers pathways for alternative treatments o...
Small (Weinheim an der Bergstrasse, Germany)
Jan 13, 2025
Magnetic microrobots are significant platforms for targeted drug delivery, among which sperm-inspired types have attracted much attention due to their flexible undulation. However, mass production of sperm-like soft magnetic microrobots with high-spe...
Nanocarriers (NCs) have emerged as a revolutionary approach in targeted drug delivery, promising to enhance drug efficacy and reduce toxicity through precise targeting and controlled release mechanisms. Despite their potential, the clinical adoption ...
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