AIMC Topic: Spectrometry, Fluorescence

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Fluorescence-based spectrometric and imaging methods and machine learning analyses for microbiota analysis.

Mikrochimica acta
Most microbiota determination (skin, gut, soil, etc.) are currently conducted in a laboratory using expensive equipment and lengthy procedures, including culture-dependent methods, nucleic acid amplifications (including quantitative PCR), DNA microar...

Single-Component Double-Emissive Ratiometric Probe: Toward Machine Learning Driven Detection and Discrimination of Neurological Biomarkers.

Analytical chemistry
This study presents an attractive single-component ratiometric fluorescent sensor that utilizes the oxidation of BSA-protected Au nanoclusters (BSA-Au NCs) by -Bromosuccinimide (NBS) to detect catecholamine neurotransmitters and their metabolites, wh...

Integration of the fluorescence based portable device with the AI tools for the real-time monitoring of oral mucosal lesions.

Scientific reports
There is a need for non-invasive, sensitive, real-time, and user-friendly optical devices integrated with artificial intelligence (AI) based tools for the detection of oral mucosal lesions at early stage. Research on the development of optical device...

Deep machine learning-assisted MOF@COF fluorescence/colorimetric dual-mode intelligent ratiometric sensing platform for sensitive glutathione detection.

Talanta
Glutathione (GSH) levels have been linked to aging and the pathogenesis of various diseases, highlighting the necessity for the development of sensitive analytical methods for GSH to facilitate disease diagnosis and treatment. In this study, we synth...

Ratiometric, 3D Fluorescence Spectrum with Abundant Information for Tetracyclines Discrimination via Dual Biomolecules Recognition and Deep Learning.

Analytical chemistry
Tetracyclines are widely used in bacteria infection treatment, while the subtle chemical differences between tetracyclines make it a challenge to accurate discrimination via biosensors. A 3D fluorescence spectrum can provide fingerprint structure inf...

Rapid diagnosis of lung cancer by multi-modal spectral data combined with deep learning.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Lung cancer is a malignant tumor that poses a serious threat to human health. Existing lung cancer diagnostic techniques face the challenges of high cost and slow diagnosis. Early and rapid diagnosis and treatment are essential to improve the outcome...

Machine Learning-Assisted Chemical Tongues Based on Dual-channel Inclusion Complexes for Rapid Identification of Nonsteroidal Anti-inflammatory Drugs in Food.

ACS sensors
The improper application of nonsteroidal anti-inflammatory drugs (NSAIDs) presents significant health hazards via vector food contamination. A critical limitation of these traditional existing approaches is their inability to concurrently discern and...

Emerging applications of fluorescence excitation-emission matrix with machine learning for water quality monitoring: A systematic review.

Water research
Fluorescence excitation-emission matrix (FEEM) spectroscopy is increasingly utilized in water quality monitoring due to its rapid, sensitive, and non-destructive measurement capabilities. The integration of machine learning (ML) techniques with FEEM ...

Excited state kinetics of tryptophan and NAD(P)H in blood plasma of normal and abnormal liver conditions: A tool to understand the metabolic changes and classification.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Early diagnosis at the metabolomic level is crucial for the treatment of liver cirrhosis and hepatocellular carcinoma (HCC). In this study, attempts were made to investigate the excited-state kinetics of intrinsic fluorophores, tryptophan and nicotin...