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Receptors, Androgen

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D-Aspartate amends reproductive performance of aged roosters by changing gene expression and testicular histology.

Reproduction, fertility, and development Jun 1, 2018
Male broiler breeders (n=32) of 55 weeks of age were administered four different doses of capsulated d-aspartate (DA; 0, 100, 200 or 300mgkg-1day-1, p.o. (DA0, DA100, DA200 and DA300 respectively)) for 12 successive weeks to assess reproductive perfo...
Spermatogenesis Receptors, N-Methyl-D-Aspartate Receptors, Androgen Cholesterol Side-Chain Cleavage Enzyme Drosophila Proteins Reproduction Proliferating Cell Nuclear Antigen D-Aspartic Acid Testis Male Animals Chickens Gene Expression Semen Analysis
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A big data approach with artificial neural network and molecular similarity for chemical data mining and endocrine disruption prediction.

Indian journal of pharmacology Jan 1, 2018
CONTEXT: Chemical toxicity prediction at early stage drug discovery phase has been researched for years, and newest methods are always investigated. Research data comprising chemical physicochemical properties, toxicity, assay, and activity details c...
Models, Theoretical Data Mining Big Data Endocrine Disruptors Receptors, Estrogen Receptors, Androgen Inhibitory Concentration 50 Machine Learning Drug Discovery Animals Humans Neural Networks, Computer
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The co-regulators SRC-1 and SMRT are involved in interleukin-6-induced androgen receptor activation.

European cytokine network Nov 1, 2016
BACKGROUND: The androgen receptor (AR) can be stimulated by interleukin-6 (IL-6) in the absence of androgens to induce prostate cancer progression. The purpose of this study was to investigate whether the co-activator steroid receptor coactivator-1 (...
Interleukin-6 Cell Line, Tumor Male Nuclear Receptor Coactivator 1 Humans Prostatic Neoplasms Nuclear Receptor Co-Repressor 2 Neoplasm Proteins Receptors, Androgen
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[Study of FN1 and ZNF438 gene expression negatively regulated by androgen receptor in androgen-independent LNCaP cells].

Zhonghua yi xue za zhi Dec 19, 2015
OBJECTIVE: To verify whether FN1 and ZNF438 are the androgen receptor(AR) target genes in LNCaP-AI cells and investigate the effects of AR exerts on FN1 and ZNF438 gene expression.
Down-Regulation Receptors, Androgen Fibronectins Repressor Proteins Androgens Oligonucleotide Array Sequence Analysis Gene Expression Prostatic Neoplasms Blotting, Western RNA, Messenger Gene Expression Regulation, Neoplastic Cell Line, Tumor Dihydrotestosterone Male Humans
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