AIMC Topic: Receptors, Chimeric Antigen
Clear Filters Showing 11 to 15 of 15 articles
Decoding CAR T cell phenotype using combinatorial signaling motif libraries and machine learning.
Science (New York, N.Y.)
Dec 8, 2022
Chimeric antigen receptor (CAR) costimulatory domains derived from native immune receptors steer the phenotypic output of therapeutic T cells. We constructed a library of CARs containing ~2300 synthetic costimulatory domains, built from combinations ...
RCMNet: A deep learning model assists CAR-T therapy for leukemia.
Computers in biology and medicine
Sep 11, 2022
Acute leukemia is a type of blood cancer with a high mortality rate. Current therapeutic methods include bone marrow transplantation, supportive therapy, and chemotherapy. Although a satisfactory remission of the disease can be achieved, the risk of ...
CD147-specific chimeric antigen receptor T cells effectively inhibit T cell acute lymphoblastic leukemia.
Cancer letters
May 31, 2022
T cell acute lymphoblastic leukemia (T-ALL) is invasive and heterogeneous, and existing therapies are sometimes unsuccessful. Chimeric antigen receptor (CAR) T cell therapy is a breakthrough tumor treatment method, particularly for B cell acute lymph...
Deep-learning-based three-dimensional label-free tracking and analysis of immunological synapses of CAR-T cells.
eLife
Dec 17, 2020
The immunological synapse (IS) is a cell-cell junction between a T cell and a professional antigen-presenting cell. Since the IS formation is a critical step for the initiation of an antigen-specific immune response, various live-cell imaging techniq...
Advancing CAR T-cell Therapies with Artificial Intelligence: Opportunities and Challenges.
Blood cancer discovery
May 5, 2025
Artificial intelligence could enhance chimeric antigen receptor T-cell therapy outcomes through optimization of all steps, from target identification, vector design, and manufacturing to personalized data-driven clinical decisions. In this report, we...
Don't Miss the Future of Medicine
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 32006
- Neural Networks, Computer 30221
- Algorithms 27397
- Deep Learning 26901
- Artificial Intelligence 24835
- Robotics 13387
- Image Processing, Computer-Assisted 9735
- Retrospective Studies 9342
- Magnetic Resonance Imaging 6346
- Reproducibility of Results 5670
- Tomography, X-Ray Computed 4865
- Support Vector Machine 4769
- Computational Biology 4332
- Brain 4129
- Computer Simulation 3935
Recent Journals
- Scientific reports 6775
- Sensors (Basel, Switzerland) 4794
- PloS one 4200
- Neural networks : the official journal of the International Neural Network Society 3026
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1916
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1378
- IEEE journal of biomedical and health informatics 1172
- Journal of chemical information and modeling 1064
- Nature communications 1044
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 873
- Journal of medical Internet research 861
- Briefings in bioinformatics 853