AIMC Topic: Receptors, Dopamine D3
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Decoding the Structure-Activity Relationship of the Dopamine D3 Receptor-Selective Ligands Using Machine and Deep Learning Approaches.
Journal of chemical information and modeling
Jun 9, 2025
Dysfunctions of the dopamine D2 and D3 receptors (D2 and D3) are implicated in neuropsychiatric conditions such as Parkinson's disease, schizophrenia, and substance use disorders (SUDs). Evidence indicates that D3-selective ligands can effectively mo...
Threshold of Dopamine D2/3 Receptor Occupancy for Hyperprolactinemia in Older Patients With Schizophrenia.
The Journal of clinical psychiatry
Dec 1, 2016
OBJECTIVE: Although hyperprolactinemia carries a long-term risk of morbidity, the threshold of dopamine D2/3 receptor (D2/3R) occupancy for hyperprolactinemia has not been investigated in older patients with schizophrenia. Data were taken from a posi...
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