AIMC Topic: Silicone Oils

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Application of one-class classification using deep learning technique improves the classification of subvisible particles.

Journal of pharmaceutical sciences
Capturing subvisible particles using flow imaging microscopy is useful for evaluating protein aggregates that may induce immunogenicity. Automated labeling is desirable to distinguish harmless components such as silicone oil (SO) from subvisible part...

Advanced Characterization of Silicone Oil Droplets in Protein Therapeutics Using Artificial Intelligence Analysis of Imaging Flow Cytometry Data.

Journal of pharmaceutical sciences
Monitoring protein particles is increasingly emphasized in the development of biopharmaceuticals due to potential immunogenicity. Accurate quantitation of protein particles is complicated by silicone oil droplets, a common pharmaceutical component in...

Performance assessment of gas-phase toluene removal in one- and two-liquid phase biotrickling filters using artificial neural networks.

Chemosphere
The main aim of this work is to study gas-phase toluene removal in one- and two-liquid phase biotrickling filters (O/TLP-BTF) and model the BTF performance using artificial neural networks (ANNs). The TLP-BTF was operated for 60 d in the presence of ...

Comparative Analysis of Macular and Optic Disc Perfusion Pre and Post Silicone Oil Removal: A Machine Learning Approach.

Studies in health technology and informatics
In the realm of ophthalmic surgeries, silicone oil is often utilized as a tamponade agent for repairing retinal detachments, but it necessitates subsequent removal. This study harnesses the power of machine learning to analyze the macular and optic d...