Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Mar 28, 2025
Near-infrared (NIR) spectroscopy has been widely used in nondestructive detection of fruit internal quality. However, the biological variability of fruit would change their texture, which may lead to the failure of fruit quality prediction models bui...
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Mar 20, 2025
This work presents a system, in which machine vision combined with artificial intelligence-based image analysis was used to determine the component-based particle size distribution of pharmaceutical powder blends. The blends consisted of acetylsalicy...
Predicting the solubility and lipophilicity of platinum(II, IV) complexes is essential for prioritizing potential anticancer candidates in drug discovery. This study introduces the first publicly available online model for predicting the solubility o...
IEEE journal of biomedical and health informatics
Mar 6, 2025
Solubility is not only a significant physical property of molecules but also a vital factor in small-molecule drug development. Determining drug solubility demands stringent equipment, controlled environments, and substantial human and material resou...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Feb 18, 2025
Accurate assessment of soluble solid content (SSC) in blueberries is crucial for quality evaluation. However, in real production lines, blueberries are usually in random placement and the biological heterogeneity of blueberry parts can lead to spectr...
Accurate estimation of the solubility of solid drugs (SDs) in the supercritical carbon dioxide (SC-CO) plays an essential role in the related technologies. In this study, artificial intelligence models (AIMs) by gene expression programming (GEP) and ...
In this study, the solubility of rivaroxaban, a poorly water-soluble drug, was investigated in mixed solvent systems to address challenges in pharmaceutical formulation and bioavailability enhancement. Solubility optimization is essential for the eff...
In order to provide the facilities to design the supercritical fluid (SCF) processes for micro or nanosizing of solid solute compounds such as drugs, it is essential to obtain their solubility in green solvents like pressurized CO. This important rol...
This paper investigates delivery of encapsulated drug from poly lactic-co-glycolic micro-/nano-particles. Experimental data collected from about 50 papers are analyzed by machine learning algorithms including linear regression, principal component an...
Lipid-based formulations are essential for enhancing drug solubility and bioavailability, yet selecting optimal lipid excipients for specific drugs remains challenging. This study introduces Sol_ME, a machine learning-based model designed to predict ...
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