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Stereoisomerism

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The use of marine-derived fungi for preparation of enantiomerically pure alcohols.

Applied microbiology and biotechnology
A highly enantioselective and minimally polluting approach to optically pure chiral alcohols is developed using cheap, readily available and sustainable marine-derived fungi as catalysts. An evaluation of the synthetic potential of 13 Chinese marine ...

Quantification of the 3α and 3β epimers of 25-hydroxyvitamin D in dried blood spots by LC-MS/MS using artificial whole blood calibration and chemical derivatization.

Talanta
While the biological function of the 3α epimer of 25-hydroxyvitamin D (25(OH)D) remains unknown, its presence needs to be accurately captured and separated from the main 3β epimer, to avoid positive bias in vitamin D status analyses. Several recent L...

[Plasma ibuprofen enantiomers and their pharmacokinetics in Beagle dogs determined by HPLC].

Yao xue xue bao = Acta pharmaceutica Sinica
A chiral high-performance liquid chromatography method was developed for the simultaneous determination of ibuprofen enantiomers in dog plasma. It was used to study the pharmacokinetics in the Beagle dog after intravenous administration of racemic-ib...