AIMC Topic: Technology, Pharmaceutical
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Stereolithography 3D printing technology in pharmaceuticals: a review.
Drug development and industrial pharmacy
Oct 29, 2021
Three-dimensional printing (3DP) technology is an innovative tool used in manufacturing medical devices, producing alloys, replacing biological tissues, producing customized dosage forms and so on. Stereolithography (SLA), a 3D printing technique, is...
Use of machine learning in prediction of granule particle size distribution and tablet tensile strength in commercial pharmaceutical manufacturing.
International journal of pharmaceutics
Sep 29, 2021
In the manufacturing of pharmaceutical Oral Solid Dosage (OSD) forms, Particle Size Distribution (PSD) and Tensile Strength (TS) are common in-process tests that are controlled in order to achieve the quality targets of the end-product. The Quality b...
Machine learning predicts 3D printing performance of over 900 drug delivery systems.
Journal of controlled release : official journal of the Controlled Release Society
Jul 30, 2021
Three-dimensional printing (3DP) is a transformative technology that is advancing pharmaceutical research by producing personalized drug products. However, advances made via 3DP have been slow due to the lengthy trial-and-error approach in optimizati...
Patentability challenges associated with emerging pharmaceutical technologies.
Pharmaceutical patent analyst
Jul 13, 2021
According to the recent patent filing trends, it has been observed that certain pharmaceutical technologies are more popular than others and are commonly referred to as emerging technologies. The emerging technologies in the pharmaceutical sector inc...
Disrupting 3D printing of medicines with machine learning.
Trends in pharmacological sciences
Jul 5, 2021
3D printing (3DP) is a progressive technology capable of transforming pharmaceutical development. However, despite its promising advantages, its transition into clinical settings remains slow. To make the vital leap to mainstream clinical practice an...
Deep Learning in Virtual Screening: Recent Applications and Developments.
International journal of molecular sciences
Apr 23, 2021
Drug discovery is a cost and time-intensive process that is often assisted by computational methods, such as virtual screening, to speed up and guide the design of new compounds. For many years, machine learning methods have been successfully applied...
Industry 4.0 for pharmaceutical manufacturing: Preparing for the smart factories of the future.
International journal of pharmaceutics
Mar 29, 2021
Over the last two centuries, medicines have evolved from crude herbal and botanical preparations into more complex manufacturing of sophisticated drug products and dosage forms. Along with the evolution of medicines, the manufacturing practices for t...
Best practices for artificial intelligence in life sciences research.
Drug discovery today
Jan 22, 2021
We describe 11 best practices for the successful use of artificial intelligence and machine learning in pharmaceutical and biotechnology research at the data, technology and organizational management levels.
M3DISEEN: A novel machine learning approach for predicting the 3D printability of medicines.
International journal of pharmaceutics
Sep 20, 2020
Artificial intelligence (AI) has the potential to reshape pharmaceutical formulation development through its ability to analyze and continuously monitor large datasets. Fused deposition modeling (FDM) three-dimensional printing (3DP) has made signifi...
Data-Driven Modeling of the Bicalutamide Dissolution from Powder Systems.
AAPS PharmSciTech
Mar 31, 2020
Low solubility of active pharmaceutical compounds (APIs) remains an important challenge in dosage form development process. In the manuscript, empirical models were developed and analyzed in order to predict dissolution of bicalutamide (BCL) from sol...
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