AIMC Topic: Xenopus Proteins

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Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold.

Science (New York, N.Y.) Jun 10, 2022
INTRODUCTION The nuclear pore complex (NPC) is the molecular conduit in the nuclear membrane of eukaryotic cells that regulates import and export of biomolecules between the nucleus and the cytosol, with vertebrate NPCs ~110 to 125 MDa in molecular m...
Artificial Intelligence Software Animals Oocytes Protein Conformation Cryoelectron Microscopy Nuclear Pore Complex Proteins Cytosol Xenopus laevis Protein Subunits Xenopus Proteins Nuclear Pore
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Deep learning is widely applicable to phenotyping embryonic development and disease.

Development (Cambridge, England) Nov 5, 2021
Genome editing simplifies the generation of new animal models for congenital disorders. However, the detailed and unbiased phenotypic assessment of altered embryonic development remains a challenge. Here, we explore how deep learning (U-Net) can auto...
Neural Networks, Computer Phenotype Animals Deep Learning Image Processing, Computer-Assisted Mice Disease Models, Animal Mutation Microscopy Embryonic Development Neurodevelopmental Disorders Xenopus laevis Polycystic Kidney Diseases Craniofacial Abnormalities Xenopus Proteins
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