AI Medical Compendium Topic

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Deep learning is widely applicable to phenotyping embryonic development and disease.

Development (Cambridge, England)
Genome editing simplifies the generation of new animal models for congenital disorders. However, the detailed and unbiased phenotypic assessment of altered embryonic development remains a challenge. Here, we explore how deep learning (U-Net) can auto...

Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold.

Science (New York, N.Y.)
INTRODUCTION The nuclear pore complex (NPC) is the molecular conduit in the nuclear membrane of eukaryotic cells that regulates import and export of biomolecules between the nucleus and the cytosol, with vertebrate NPCs ~110 to 125 MDa in molecular m...