Artificial Intelligence Medical Compendium

Explore the latest research on artificial intelligence and machine learning in medicine.

Showing 2,051 to 2,060 of 200,859 articles

Frequency-Specific Alterations of Spontaneous Brain Activity in Stroke Patients with Upper Limb Motor Dysfunction: A Multi-Metric rs-fMRI and Machine Learning Study.

Brain research bulletin
BACKGROUND: Post-stroke upper limb motor dysfunction is associated with complex alterations in brain function, but the frequency-specific characteristics of spontaneous local neural activity remain incompletely understood. This study investigated mul... read more 

EEG monitoring in the operating room: current uses and perspectives - a narrative review.

Anaesthesia, critical care & pain medicine
CONTEXT AND IMPORTANCE: With over 300 million surgeries performed under general anaesthesia annually, optimising perioperative brain health has become a critical public health priority. Electroencephalogram (EEG) monitoring, initially conceived to pr... read more 

Does lens opacity matter? The effect of cataract on deep learning based cardiovascular disease risk scores from fundus photos.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)
PURPOSE: To investigate the effect of cataracts on a deep learning (DL) model for cardiovascular disease (CVD) risk prediction. METHODS: This retrospective, dual-cohort study analyzed fundus images at baseline, 1, and 6-months post-cataract surgery f... read more 

Digital and technology-enabled approaches in dietary assessment: addressing bias, error, and feasibility in population- and community-based research.

Advances in nutrition (Bethesda, Md.)
Dietary intake data are essential for understanding diet-disease relationships, informing policy, and evaluating nutrition interventions. This is particularly challenging in population-and community-based research, where varying dietary patterns, mot... read more 

AI-enhanced cardiac digital twins extend drug proarrhythmic risk assessment through experimental data uncertainty propagation and overdose exploration: A loperamide case study.

Regulatory toxicology and pharmacology : RTP
Drug-induced QT interval prolongation is a key biomarker of proarrhythmic risk and central to drug cardiac safety evaluation alongside in vitro assays and animal studies, yet current preclinical frameworks provide limited insight into how experimenta... read more 

TF-DWGNet: a directed weighted graph neural network with tensor fusion for multi-omics cancer subtype classification.

NAR genomics and bioinformatics
Integration and analysis of multi-omics data provide valuable insights for improving cancer subtype classification. However, such data are inherently heterogeneous, high-dimensional, and exhibit complex intra- and inter-modality dependencies. Graph n... read more 

Predicting the Host-Guest Binding Gibbs Free Energy for Anion Guests.

Journal of computational chemistry
Host-guest chemistry is an emerging approach in the design of functional molecular systems, with growing potential in areas such as targeted drug delivery, sensing, and adaptive materials. However, the development of new hosts and finding new guests ... read more 

Entropy Fusion DNA: Alignment-Free Gene Fusion Detection through Entropy and Mutual Information Descriptors

bioRxiv
Gene fusions are clinically relevant genomic alterations and key cancer biomarkers. Their computational detection remains dominated by alignment-based pipelines, whose reliance on read mapping, reference annotations, and heuristic filtering makes the... read more 

Cooperative FOXA1-HNF4A binding emerges from motif spacing and nucleosome architecture

bioRxiv
The pioneer factor hypothesis posits that specialized transcription factors access nucleosomal DNA to enable binding of secondary factors, implying a hierarchical mechanism of chromatin opening. However, recent evidence indicates that cooperative bin... read more 

Explainable machine learning reveals an RBP regulatory logic of exon skipping

bioRxiv
RNA binding proteins (RBPs) regulate the life cycle of an mRNA, often through RBP-RNA interactions. This life cycle includes splicing, whereby the intronic sequence of a pre-mRNA is removed and the exons are joined together. However, the patterns of ... read more