PURPOSE: This systematic review and meta-analysis evaluated the performance of imaging-based artificial intelligence (AI) models in diagnosing preoperative cervical lymph node metastasis (LNM) in clinically node-negative (cN0) papillary thyroid carci... read more
Mammalian perfusion culture offers high productivity for complex biologics but presents operational challenges in maintaining process stability. Real-time monitoring is essential to address such challenges while traditional analytical methods often f... read more
Conventional diagnostic and therapeutic approaches in orthopedics are frequently time intensive and associated with elevated rates of diagnostic error, underscoring the urgent need for more efficient tools to improve the current situation. Recently, ... read more
Molecularly imprinted photonic crystal hydrogel (MIPCH) serves as a highly effective platform for the sensitive and selective detection of various analyte molecules. In this study, we present a smartphone-based inverse opal MIPCH (IOMIPCH) sensor des... read more
RNA-based therapeutics are currently at the forefront of the biopharmaceutical industry because of their safety, efficacy, and shortened time from disease discovery to therapy development. Microfluidic electrophoresis provides a great analytical plat... read more
BACKGROUND: Prediction of postoperative patient-reported outcomes and risk for revision surgery after total hip arthroplasty (THA) or total knee arthroplasty (TKA) can inform clinical decision-making, health resource allocation, and care planning. Ma... read more
OBJECTIVE: The application of digital phenotyping in personality research leverages smartphone-generated data to quantify individual differences in personality constructs. It can be conceptualized as an extension of Experience Sampling Methods (ESMs)... read more
Receptor tyrosine kinases (RTKs) are high-affinity membrane-anchored receptors involved in cellular communication via various ligands and manage numerous biological processes such as cell growth, differentiation, and metabolism. However, dysregulatio... read more
Nonalcoholic fatty liver disease (NAFLD) is emerging as the leading cause of chronic liver disease in many regions, particularly in association with the rising prevalence of Metabolic syndrome (MetS), affecting more than 30% of the population worldwi... read more
BackgroundVarious methods have been reported for improving the water-insoluble drugs in oral administration formulations. Among them, amorphization has been attracting attention and developed as a method for solubilizing API (active pharmaceutical in... read more
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