Preoperative DBT-based radiomics for predicting axillary lymph node metastasis in breast cancer: a multi-center study.

Journal: BMC medical imaging
Published Date: May 19, 2025

Abstract

BACKGROUND: In the prognosis of breast cancer, the status of axillary lymph nodes (ALN) is critically important. While traditional axillary lymph node dissection (ALND) provides comprehensive information, it is associated with high risks. Sentinel lymph node biopsy (SLND), as an alternative, is less invasive but still poses a risk of overtreatment. In recent years, digital breast tomosynthesis (DBT) technology has emerged as a new precise diagnostic tool for breast cancer, leveraging its high detection capability for lesions obscured by dense glandular tissue.

Authors

  • Shuyan He
    Guangzhou Medical University, Panyu District, Guangzhou, Guangdong, China. 1012027045@qq.com.
  • Biao Deng
    Department of Cardiothoracic Surgery, Affiliated Hospital of Guangdong Medical University, Xiashan District, Zhanjiang, Guangdong, China. 15760562638@163.com.
  • Jiaqi Chen
    Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.
  • Jiamin Li
    Guangdong Medical Universiy, Xiashan District, Zhanjiang, Guangdong, China.
  • Xuefeng Wang
    Department of Advanced Manufacturing and Robotics, College of Engineering, Peking University, Beijing 100871, China.
  • Guanxing Li
    Department of Radiology, Guangdong Women and Children Hospital, Guangzhou, China.
  • Siyu Long
    Department of Radiology, Guangdong Women and Children Hospital, Guangzhou, China.
  • Jian Wan
  • Yan Zhang
    Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, 110032, China.

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