Establishing a Deep Learning Model That Integrates Pretreatment and Midtreatment Computed Tomography to Predict Treatment Response in Non-Small Cell Lung Cancer.

Journal: International journal of radiation oncology, biology, physics
Published Date:

Abstract

PURPOSE: Patients with identical stages or similar tumor volumes can vary significantly in their responses to radiation therapy (RT) due to individual characteristics, making personalized RT for non-small cell lung cancer (NSCLC) challenging. This study aimed to develop a deep learning model by integrating pretreatment and midtreatment computed tomography (CT) to predict the treatment response in NSCLC patients.

Authors

  • Xuming Chen
    Department of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Fanrui Meng
    Department of Cellular and Physiological Sciences, LSI Imaging, Life Sciences Institute, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Ping Zhang
    Department of Computer Science and Engineering, The Ohio State University, USA.
  • Lei Wang
    Department of Nursing, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
  • Shengyu Yao
    Department of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Chengyang An
    Department of Automation, Shanghai Jiao Tong University, Shanghai, China.
  • Hui Li
    Department of Ophthalmology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
  • Dongfeng Zhang
    Information Technology Research Center, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.
  • Hongxia Li
    Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan Province, People's Republic of China.
  • Jie Li
    Guangdong-Hong Kong-Macao Greater Bay Area Artificial Intelligence Application Technology Research Institute, Shenzhen Polytechnic University, Shenzhen, China.
  • Lisheng Wang
    Department of Automation, Shanghai Jiaotong University, China.
  • Yong Liu
    Department of Critical care medicine, Shenzhen Hospital, Southern Medical University, Guangdong, Shenzhen, China.