The Cost-Effectiveness of an Artificial Intelligence-Based Population-Wide Screening Program for Primary Open-Angle Glaucoma in The Netherlands.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
Published Date: Jun 26, 2025

Abstract

OBJECTIVES: Population-wide screening for primary open-angle glaucoma (glaucoma) is typically not cost-effective because of low prevalence and high costs. We evaluated the cost-effectiveness of repeated artificial intelligence (AI)-based glaucoma screening using fundus photos in the Dutch population aged 50 to 75, compared with opportunistic case finding.

Authors

  • Bart-Jan Boverhof
    Erasmus School of Health Policy & Management, Erasmus University Rotterdam, Rotterdam, The Netherlands.
  • Isaac Corro Ramos
    Institute for Medical Technology Assessment/Erasmus School of Health Policy & Management, Erasmus University Rotterdam, Rotterdam, The Netherlands.
  • Koen A Vermeer
    Rotterdam Ophthalmic Institute, the Rotterdam Eye Hospital, Rotterdam, The Netherlands.
  • Victor A de Vries
    Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands; Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Caroline C W Klaver
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands; Department of Ophthalmology, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Ophthalmology, Radboud University Medical Center, Nijmegen, The Netherlands; Institute for Molecular and Clinical Ophthalmology, Basel, Switzerland.
  • Wishal D Ramdas
    Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Hans G Lemij
    Rotterdam Eye Hospital, Rotterdam, The Netherlands.
  • Maureen Rutten-van Mölken
    Erasmus School of Health Policy and Management, Erasmus University, Rotterdam, The Netherlands; Institute for Medical Technology Assessment, Rotterdam, The Netherlands.

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