AIMC Topic: Glaucoma, Open-Angle

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Identification of diagnostic biomarkers and dissecting immune microenvironment with crosstalk genes in the POAG and COVID-19 nexus.

Scientific reports Jul 12, 2025
An underlying association between primary open-angle glaucoma (POAG) and COVID-19 has been hypothesized, but the causal link and shared mechanisms remain unclear. This study integrates epidemiological and bioinformatics approaches to investigate thei...
Humans Machine Learning COVID-19 Biomarkers Female Gene Regulatory Networks Computational Biology Transcription Factors MicroRNAs Glaucoma, Open-Angle SARS-CoV-2 Risk Factors Aged Male Middle Aged
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Screening of Glaucoma in High-Risk Minority Populations.

Journal of glaucoma Jun 26, 2025
PRECIS: This chapter reviews the current recommendations on screening for open angle glaucoma in Black and Hispanic populations. Strategies for increasing case-finding and decreasing cost, with emphasis on evolving technologies, are presented.
Hispanic or Latino Minority Groups Black or African American White Glaucoma, Open-Angle Humans Risk Factors Intraocular Pressure Prevalence United States Mass Screening
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Mathematical Modeling and Artificial Intelligence to Explore Connections Between Glaucoma and the Gut Microbiome.

Medicina (Kaunas, Lithuania) Feb 14, 2025
Glaucoma is a major cause of irreversible blindness, with primary open-angle glaucoma (POAG) being the most prevalent form. While elevated intraocular pressure (IOP) is a well-known risk factor for POAG, emerging evidence suggests that the human gut...
Artificial Intelligence Humans Models, Theoretical Glaucoma Gastrointestinal Microbiome Glaucoma, Open-Angle
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Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom.

American journal of ophthalmology Jan 13, 2025
PURPOSE: A previously developed machine-learning approach with Kalman filtering technology accurately predicted the disease trajectory for patients with various glaucoma types and severities using clinical trial data. This study assesses performance ...
Retrospective Studies Female Reproducibility of Results Aged Intraocular Pressure Humans Machine Learning Visual Fields Visual Field Tests Glaucoma, Open-Angle Male Middle Aged Follow-Up Studies Predictive Value of Tests United Kingdom
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Detection of glaucoma progression on longitudinal series of en-face macular optical coherence tomography angiography images with a deep learning model.

The British journal of ophthalmology Nov 22, 2024
BACKGROUND/AIMS: To design a deep learning (DL) model for the detection of glaucoma progression with a longitudinal series of macular optical coherence tomography angiography (OCTA) images.
Optic Disk Retinal Ganglion Cells Visual Fields Visual Field Tests Fluorescein Angiography Disease Progression Deep Learning ROC Curve Follow-Up Studies Tomography, Optical Coherence Macula Lutea Retinal Vessels Glaucoma, Open-Angle Humans Retrospective Studies Female Aged Intraocular Pressure Male Middle Aged
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Identifying Factors Associated With Fast Visual Field Progression in Patients With Ocular Hypertension Based on Unsupervised Machine Learning.

Journal of glaucoma Aug 5, 2024
PRCIS: We developed unsupervised machine learning models to identify different subtypes of patients with ocular hypertension in terms of visual field (VF) progression and discovered 4 subtypes with different trends of VF worsening. We then identified...
Visual Field Tests Glaucoma, Open-Angle Ocular Hypertension Disease Progression Follow-Up Studies Unsupervised Machine Learning Vision Disorders Visual Fields Cross-Sectional Studies Intraocular Pressure Male Middle Aged Humans Female Risk Factors Aged
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Progression or Aging? A Deep Learning Approach for Distinguishing Glaucoma Progression From Age-Related Changes in OCT Scans.

American journal of ophthalmology May 3, 2024
PURPOSE: To develop deep learning (DL) algorithm to detect glaucoma progression using optical coherence tomography (OCT) images, in the absence of a reference standard.
Humans Neural Networks, Computer Nerve Fibers Glaucoma Optic Disk Algorithms Retinal Ganglion Cells Middle Aged Retrospective Studies Female Visual Fields Disease Progression Optic Nerve Diseases Glaucoma, Open-Angle Aged Deep Learning Follow-Up Studies Intraocular Pressure Tomography, Optical Coherence Male Aging
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Recognition of Glaucomatous Fundus Images Using Machine Learning Methods Based on Optic Nerve Head Topographic Features.

Journal of glaucoma Mar 29, 2024
PRCIS: Machine learning classifiers are an effective approach to detecting glaucomatous fundus images based on optic disc topographic features making it a straightforward and effective approach.
Glaucoma Machine Learning Retrospective Studies Female Aged Optic Disk Intraocular Pressure Humans Optic Nerve Diseases Male Glaucoma, Open-Angle Middle Aged Case-Control Studies Fundus Oculi
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Machine learning-assisted prediction of trabeculectomy outcomes among patients of juvenile glaucoma by using 5-year follow-up data.

Indian journal of ophthalmology Mar 8, 2024
OBJECTIVE: To develop machine learning (ML) models, using pre and intraoperative surgical parameters, for predicting trabeculectomy outcomes in the eyes of patients with juvenile-onset primary open-angle glaucoma (JOAG) undergoing primary surgery.
Treatment Outcome Follow-Up Studies Glaucoma, Open-Angle Gonioscopy Trabeculectomy Humans Male Machine Learning Adolescent Retrospective Studies Time Factors Female Child Young Adult ROC Curve Adult Intraocular Pressure
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Prediction of Visual Field Progression with Baseline and Longitudinal Structural Measurements Using Deep Learning.

American journal of ophthalmology Feb 12, 2024
PURPOSE: Identifying glaucoma patients at high risk of progression based on widely available structural data is an unmet task in clinical practice. We test the hypothesis that baseline or serial structural measures can predict visual field (VF) progr...
Visual Fields Visual Field Tests Optic Nerve Diseases Glaucoma, Open-Angle Disease Progression Area Under Curve Female Humans Deep Learning Aged Tomography, Optical Coherence ROC Curve Intraocular Pressure Glaucoma Follow-Up Studies Nerve Fibers Male Vision Disorders Algorithms Optic Disk Middle Aged Retrospective Studies Retinal Ganglion Cells
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