Stress Testing of an Artificial Pancreas System With Pizza and Exercise Leads to Improvements in the System's Fuzzy Logic Controller.

Journal: Journal of diabetes science and technology
PMID:

Abstract

BACKGROUND: Under controlled conditions, the Dose Safety artificial pancreas (AP) system controller, which utilizes "fuzzy logic" (FL) methodology to calculate and deliver appropriate insulin dosages based on changes in blood glucose, successfully managed glycemic excursions. The aim of this study was to show whether stressing the system with pizza (high carbohydrate/high fat) meals and exercise would reveal deficits in the performance of the Dose Safety FL controller (FLC) and lead to improvements in the dosing matrix.

Authors

  • Richard Mauseth
    Department of Pediatrics, University of Washington, Seattle, WA, USA Dose Safety, Inc, Seattle, WA, USA richardmausethmd@msn.com.
  • Sandra M Lord
    Benaroya Research Institute, Seattle, WA, USA.
  • Irl B Hirsch
    School of Medicine, University of Washington, Seattle, WA, USA.
  • Robert C Kircher
    Dose Safety, Inc, Seattle, WA, USA.
  • Don P Matheson
    Dose Safety, Inc, Seattle, WA, USA.
  • Carla J Greenbaum
    Benaroya Research Institute, Seattle, WA, USA.