Machine learning to predict the long-term risk of myocardial infarction and cardiac death based on clinical risk, coronary calcium, and epicardial adipose tissue: a prospective study.

Journal: Cardiovascular research
Published Date:

Abstract

AIMS: Our aim was to evaluate the performance of machine learning (ML), integrating clinical parameters with coronary artery calcium (CAC), and automated epicardial adipose tissue (EAT) quantification, for the prediction of long-term risk of myocardial infarction (MI) and cardiac death in asymptomatic subjects.

Authors

  • Frederic Commandeur
  • Piotr J Slomka
    Department of Imaging, Medicine, and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California Piotr.Slomka@cshs.org.
  • Markus Goeller
    Biomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Taper building, A238, 8700 Beverly Blvd, Los Angeles, 90048, USA.
  • Xi Chen
    Department of Critical care medicine, Shenzhen Hospital, Southern Medical University, Guangdong, Shenzhen, China.
  • Sebastien Cadet
  • Aryabod Razipour
    Biomedical Imaging Research Institute (P.A.M., F.C., X.C., M.G., A.R., D.D.), Cedars-Sinai Medical Center, Los Angeles, CA.
  • Priscilla McElhinney
    Department of Biomedical Sciences, Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, 116 N Robertson Blvd, Los Angeles, CA 90048, USA.
  • Heidi Gransar
    Departments of Imaging, Medicine, and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.
  • Stephanie Cantu
    Department of Imaging and Medicine and the Smidt Heart Institute (E.E., S.C., H.G., S.C., R.J.H.M., P.J.S., B.K.T., D.S.B.), Cedars-Sinai Medical Center, Los Angeles, CA.
  • Robert J H Miller
    Department of Imaging and Medicine and the Smidt Heart Institute (E.E., S.C., H.G., S.C., R.J.H.M., P.J.S., B.K.T., D.S.B.), Cedars-Sinai Medical Center, Los Angeles, CA.
  • Alan Rozanski
    Division of Cardiology, Mount Sinai St Lukes Hospital, New York, NY (A.R.).
  • Stephan Achenbach
    Department of Cardiology, Friedrich-Alexander Universitat Erlangen-Nurnberg, Erlangen, Germany.
  • Balaji K Tamarappoo
  • Daniel S Berman
    Departments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Damini Dey
    Departments of Imaging and Medicine, and Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Taper A238, Los Angeles, CA, 90048, USA.