A deep look into radiomics.

Journal: La Radiologia medica
PMID:

Abstract

Radiomics is a process that allows the extraction and analysis of quantitative data from medical images. It is an evolving field of research with many potential applications in medical imaging. The purpose of this review is to offer a deep look into radiomics, from the basis, deeply discussed from a technical point of view, through the main applications, to the challenges that have to be addressed to translate this process in clinical practice. A detailed description of the main techniques used in the various steps of radiomics workflow, which includes image acquisition, reconstruction, pre-processing, segmentation, features extraction and analysis, is here proposed, as well as an overview of the main promising results achieved in various applications, focusing on the limitations and possible solutions for clinical implementation. Only an in-depth and comprehensive description of current methods and applications can suggest the potential power of radiomics in fostering precision medicine and thus the care of patients, especially in cancer detection, diagnosis, prognosis and treatment evaluation.

Authors

  • Camilla Scapicchio
    Academic Radiology, Department of Translational Research, University of Pisa, Via Roma 67, 56126, Pisa, Italy. camilla.scapicchio@med.unipi.it.
  • Michela Gabelloni
    Academic Radiology, Department of Translational Research, University of Pisa, Via Roma 67, 56126, Pisa, Italy.
  • Andrea Barucci
    Institute of Applied Physics "Nello Carrara", Italian National Research Council, via Madonna del Piano 10, Sesto Fiorentino, I-50019, Italy. p.matteini@ifac.cnr.it.
  • Dania Cioni
    Academic Radiology, Department of Surgical, Medical, Molecular Pathology and Emergency Medicine, University of Pisa, Via Roma 67, 56126, Pisa, Italy.
  • Luca Saba
    Department of Radiology, A.O.U., Italy.
  • Emanuele Neri
    Department of Radiological Sciences, University of Pisa, Via Savi 10, 56126 Pisa, Italy.