Incorporating artificial intelligence in urology: Supervised machine learning algorithms demonstrate comparative advantage over nomograms in predicting biochemical recurrence after prostatectomy.

Journal: The Prostate
PMID:

Abstract

OBJECTIVE: After radical prostatectomy (RP), one-third of patients will experience biochemical recurrence (BCR), which is associated with subsequent metastasis and cancer-specific mortality. We employed machine learning (ML) algorithms to predict BCR after RP, and compare them with traditional regression models and nomograms.

Authors

  • Yu Guang Tan
    Department of Urology, Sengkang General Hospital, Singapore.
  • Andrew H S Fang
    Singhealth Polyclinics, Singapore, Singapore.
  • Jay K S Lim
    Department of Urology, Singapore General Hospital, Singapore, Singapore.
  • Farhan Khalid
    Department of Urology, Singapore General Hospital, Singapore, Singapore.
  • Kenneth Chen
    Department of Urology, Singapore General Hospital, Singapore.
  • Henry S S Ho
    Department of Urology, Singapore General Hospital, Singapore, Singapore.
  • John S P Yuen
    Department of Urology, Singapore General Hospital, Singapore, Singapore.
  • Hong Hong Huang
    Department of Urology, Singapore General Hospital, Singapore.
  • Kae Jack Tay
    Department of Urology, Singapore General Hospital, Singapore.